Table 5 The genotype frequencies of TIMP-2 -418G > C polymorphism between the control group and patients with moyamoya disease
Characteristic | Control (n = 243) | Moyamoya (n = 107) | AOR (95% CI) | P a | P b |
|---|---|---|---|---|---|
TIMP-2 -418G > C (rs8179090) | |||||
GG | 178 (73.3) | 56 (52.3) | 1.00 (reference) | ||
GC | 61 (25.1) | 46 (43.0) | 2.33 (1.42-3.80) | <.01 | 0.02 |
CC | 4 (1.6) | 5 (4.7) | 3.53 (0.89-13.98) | 0.07 | 0.09 |
Dominant (GG vs. GC + CC) | 2.39 (1.48-3.85) | <.01 | 0.02 | ||
Recessive (GG + GC vs. CC) | 2.32 (0.60-8.96) | 0.23 | 0.23 | ||
HWE P | 0.64 | 0.24 |