| |
Deceased patientsare notincluded in mRS:
|
Deceased patientsareincluded in mRS:
|
|---|
|
Ordinal score:
|
Dichotomous indicator for dependence of support:
|
Ordinal score:
|
Dichotomous indicator for dependence of support:
|
|---|
|
SNP
|
Estimated Spearman’s Rho
|
P-value
|
Simple logistic regression
|
Multiple logistic regression
|
Estimated Spearman’s Rho
|
P-value
|
Simple logistic regression
|
Multiple logistic regression
|
|---|
|
OR (95% CI)
|
P-value
|
OR (95% CI)
|
P-value
|
OR (95% CI)
|
P-value
|
OR (95% CI)
|
P-value
|
|---|
|
SIGMAR1:
| | | | | | | | | | | | |
|
rs11559048
|
0.045
|
0.081
|
3.35 (0.80-14.1)
|
0.099
|
2.75 (0.49-15.3)
|
0.249
|
0.026
|
0.286
|
2.64 (0.63-11.1)
|
0.185
|
2.29 (0.38-13.7)
|
0.364
|
|
rs1800866
|
0.011
|
0.655
|
1.13 (0.93-1.37)
|
0.231
|
1.10 (0.88-1.36)
|
0.404
|
0.004
|
0.872
|
1.08 (0.90-1.30)
|
0.402
|
1.06 (0.85-1.31)
|
0.612
|
|
rs12001648
|
-0.012
|
0.631
|
0.94 (0.67-1.32)
|
0.712
|
0.77 (0.53-1.11)
|
0.165
|
-0.001
|
0.963
|
0.98 (0.72-1.34)
|
0.892
|
0.75 (0.53-1.07)
|
0.115
|
|
rs7036351
|
0.006
|
0.817
|
1.10 (0.89-1.33)
|
0.390
|
1.03 (0.83-1.29)
|
0.781
|
-0.007
|
0.772
|
1.04 (0.86-1.25)
|
0.722
|
0.97 (0.79-1.21)
|
0.810
|
|
rs3808873
|
0.021
|
0.436
|
1.08 (0.90-1.29)
|
0.392
|
1.11 (0.91-1.35)
|
0.290
|
0.012
|
0.636
|
1.05 (0.89-1.24)
|
0.598
|
1.07 (0.89-1.30)
|
0.457
|
|
APOD:
| | | | | | | | | | | | |
|
rs76929107
|
0.002
|
0.947
|
0.98 (0.54-1.78)
|
0.943
|
0.95 (0.49-1.82)
|
0.868
|
-0.013
|
0.582
|
0.87 (0.49-1.54)
|
0.623
|
0.92 (0.48-1.73)
|
0.790
|
|
rs5952
|
0.016
|
0.520
|
1.98 (0.28-14.1)
|
0.494
|
2.90 (0.32-26.7)
|
0.346
|
0.025
|
0.306
|
2.35 (0.39-14.1)
|
0.350
|
3.09 (0.35-27.5)
|
0.312
|
|
rs34697430
|
-0.019
|
0.460
|
0.91 (0.78-1.06)
|
0.221
|
0.91 (0.77-1.07)
|
0.243
|
0.002
|
0.946
|
0.96 (0.83-1.10)
|
0.514
|
0.92 (0.79-1.08)
|
0.295
|
|
rs7659
|
0.002
|
0.929
|
1.03 (0.88-1.22)
|
0.684
|
0.98 (0.82-1.17)
|
0.832
|
-0.005
|
0.846
|
1.02 (0.87-1.18)
|
0.842
|
0.96 (0.81-1.14)
|
0.665
|
|
rs823510
|
0.012
|
0.653
|
1.01 (0.85-1.21)
|
0.882
|
1.02 (0.84-1.23)
|
0.871
|
-0.008
|
0.742
|
0.97 (0.82-1.14)
|
0.696
|
0.97 (0.81-1.17)
|
0.764
|
- Ischemic stroke patients from Lund Stroke Register and the Sahlgenska Academy Study on Ischemic Stroke.
- mRS = modified Rankin Scale. Ordinal score comprises distinguishable categories 0–2, 3, 4, 5 and, if deceased patients are included, also category 6. Correspondingly, dichotomous indicator comprises categories 0–2 as control subjects and category 3 or above as cases.
