NEDA proportions. A) Baseline to Week 48. B). Baseline to Week 24. C). Weeks 24–48. ORs are shown with 95% confidence intervals in parentheses. aDefined as absence of both clinical (no relapses and no onset of 12-week confirmed disability progression over the interval) and MRI (no gadolinium-enhancing lesions and no new or newly-enlarging T2 hyperintense lesions) disease activity; data from patients with complete MRI results during the time interval were used for analysis of MRI disease activity. NEDA = No evidence of disease activity; MRI = magnetic resonance imaging; OR = odds ratio.