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Table 2 Association results

From: Decision tree analysis of genetic risk for clinically heterogeneous Alzheimer’s disease

Gene SNP OR STAT P MAF
APOE rs429358/rs7412 4.28 4.83 1.36E-06 0.20
HFE rs1799945 2.83 3.15 1.64E-03 0.15
PICALM rs3851179 0.47 −3.04 2.37E-03 0.42
CR1 rs6701713 0.42 −2.65 0.01 0.19
SLC6A4 rs2020942 1.81 2.63 0.01 0.40
TPH1 rs1799913 0.64 −2.02 0.04 0.44
KIAA0319 rs4504469 0.60 −2.02 0.04 0.35
CDC42BPA rs1320490 1.63 1.93 0.05 0.20
TMEM175 rs6599389 0.41 −1.81 0.07 0.08
SORL1 rs2070045 1.63 1.74 0.08 0.22
CNTNAP2 rs17236239 0.66 −1.61 0.11 0.16
ATP2C2 rs8053211 1.45 1.56 0.12 0.43
CD2AP rs9349407 1.48 1.55 0.12 0.29
TPD52 rs7814569 1.79 1.53 0.13 0.09
COMT rs4680 0.72 −1.41 0.16 0.50
C9ORF72 rs3849942 1.42 1.38 0.17 0.24
CPE rs11186856 0.33 −1.37 0.17 0.33
SORL1 rs12285364 0.42 −1.34 0.18 0.04
RIT2 rs4130047 0.70 −1.33 0.18 0.31
MOBP rs1768208 0.72 −1.3 0.19 0.29
  1. Top 20 association results in the Discovery cohort. Only APOE was significant after Bonferroni correction for multiple testing. OR – odds ratio; STAT – test statistic; MAF – minor allele frequency.