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Table 2 Association of different patient characteristics with depression (BDI) and quality of life (SF-36) scores

From: Interaction of physical function, quality of life and depression in Amyotrophic lateral sclerosis: characterization of a large patient cohort

  BDI Physical functioning Physical role Bodily pain General health Vitality Social functioning Emotional role Mental health
ALSFRS-R(p < 0.001) (p < 0.001) 0.092 - 0.731 (p < 0.01) 0.175 0.774 0.052
ALSFRS-R bulbar 0.345 - - (p < 0.01) - 0.116 0.864 - 0.555
Disease duration - - - 0.113 - - - - -
Gender - - - - - - - - -
Onset - Sig.for spinal onset (p < 0.01) Sig.for spinal onset (p < 0.001) 0.743 - - - - -
Age 0.126 0.072 - - 0.058 - (p < 0.05) - 0.292
BDI n.a. 0.132 (p < 0.001) (p < 0.05) (p < 0.001) (p < 0.001) (p < 0.001) (p < 0.001) (p < 0.001)
  1. -: p-value >0.2 in the simple regression, variable not included in the final multiple regression model
  2. n.a.: not applicable
  3. ALSFRS-R: Amyotrophic Lateral Sclerosis Functional Rating Scale – Revised
  4. BDI: Beck Depression Inventory