Table 2 Clinical and biochemical characteristics of survivor and non-survivor MMCAI patients

Gender female – n (%)

8 (33.3)

9 (34.6)

0.99

Decompressive craniectomy – n (%)

7 (29.2)

5 (19.2)

0.51

Age (years) - median (p 25–75)

47 (32–67)

66 (45–76)

0.14

Temperature (°C) - median (p 25–75)

36.5 (35.7-37.0)

37.0 (35.7-37.8)

0.26

Sodium (mEq/L)- median (p 25–75)

140 (138–145)

140 (137–146)

0.91

Glycemia (g/dL) - median (p 25–75)

133 (105–170)

135 (110–154)

0.92

Leukocytes-median*10³/mm³ (p 25–75)

12.8 (9.8-16.9)

14.4 (11.9-21.9)

0.49

PaO2 (mmHg) - median (p 25–75)

110 (101–194)

104 (85–139)

0.10

PaO2/FI0₂ ratio - median (p 25–75)

246 (192–327)

248 (175–320)

0.41

Bilirubin (mg/dl) - median (p 25–75)

0.50 (0.38-0.90)

0.53 (0.30-1.20)

0.76

Creatinine (mg/dl) - median (p 25–75)

0.80 (0.60-1.10)

1.01 (0.85-1.45)

0.052

Hemoglobin (g/dL) - median (p 25–75)

12.0 (11.3-13.8)

12.0 (11.0-15.1)

0.92

GCS score - median (p 25–75)

7 (6–8)

6 (4–8)

0.10

Lactic acid (mmol/L)-median (p 25–75)

1.25 (0.93-1.68)

1.50 (1.01-3.15)

0.08

Platelets - median*10³/mm³ (p 25–75)

227(183–308)

152 (123–190)

0.003

INR - median (p 25–75)

1.07 (1.01-1.20)

1.20 (1.07-1.48)

0.16

aPTT (seconds) - median (p 25–75)

28 (25–29)

26 (25–33)

0.96

Fibrinogen (mg/dl) - median (p 25–75)

440 (335–494)

409 (322–598)

0.71

APACHE-II score - median (p 25–75)

20 (16–25)

22 (19–29)

0.14

MMP-9 (ng/mL) - median (p 25–75)

963 (731–1218)

672 (384–1088)

0.04

MMP-10 (pg/mL) - median (p 25–75)

785 (550–1114)

1264 (608–1759)

0.02

TIMP-1 (ng/mL) - median (p 25–75)

204 (172–264)

343 (240–493)

<0.001

PAI-1 (ng/mL) - median (p 25–75)

24.0 (19.3-40.8)

51.5 (28.3-95.3)

0.02

TNF-alpha (pg/mL) - median (p 25–75)

9.25 (9.02-10.63)

12.95 (10.03-15.08)

0.01