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Table 2 Comparisons of initial NIHSS scores between statin users and non-users for unmatched and PS-matched cohorts

From: Effect of pre-stroke statin use on stroke severity and early functional recovery: a retrospective cohort study

 

Statin users

Non-users

Difference

P-value

Unmatched cohort

    

Unadjusted

4.6 (4.3–4.9)

5.4 (5.3–5.6)

0.8 (0.5–1.2)

<0.001

Adjusteda

5.7 (5.2–6.3)

6.4 (5.9–6.9)

0.7 (0.2–1.1)

0.002

PS-matched cohort

    

PS-matchedb

5.2 (4.7–5.7)

5.7 (5.4–6.0)

0.5 (0.02–1.0)

0.043

PS-stratification, decilesc

5.1 (4.7–5.6)

5.7 (5.6–5.9)

0.6 (0.1–1.1)

0.015

  1. Values are mean (95 % CI) or least-square mean (95 % CI) as appropriate
  2. aAdjusted for age, sex, body mass index, diastolic blood pressure, hemoglobin, total cholesterol, LDL cholesterol, pre-stroke modified Rankin Scale score, history of hypertension, diabetes mellitus, hyperlipidemia, atrial fibrillation, history of stroke, history of coronary artery disease, smoking, prior antiplatelet medication, anticoagulant, angiotensin receptor blocker or angiotensin converting enzyme inhibitor, beta-blocker, diuretics, calcium-channel blocker, TOAST classification, SYSO and onset to arrival time
  3. bPS-matched sample included 618 pairs with one-to-n (n ranged from one to four) matching: 618 statin users and 1585 non-users. Adjusted for hyperlipidemia, history of stroke, total cholesterol, LDL cholesterol, prior medications of any antiplatelet and ARB or ACEI, and SYSO
  4. cAdjusted for SYSO
  5. NIHSS National Institutes of Health Stroke Scale, PS Propensity score
  6. Values presented are type III estimates