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Table 4 Multivariable binary and ordinal logistic regression analyses for mRS outcome for unmatched and PS-matched cohorts

From: Effect of pre-stroke statin use on stroke severity and early functional recovery: a retrospective cohort study

 

Binary outcomea

Ordinal outcomeb

 

OR

95 % CI

p-value

OR

95 % CI

p-value

Crude analysis, unmatched cohort

1.44

(1.25–1.66)

<0.001

1.37

(1.21–1.54)

<0.001

Multivariable analysisc, unmatched cohort

1.55

(1.25–1.92)

<0.001

1.29

(1.12–1.51)

0.001

PS- matched analysisd, e

1.47

(1.16–1.88)

0.002

1.26

(1.06–1.50)

0.008

PS-stratification, decilesf

1.57

(1.25–1.96)

<0.001

1.31

(1.11–1.54)

0.001

  1. Odd ratio for statin use prior to stroke
  2. aDependent variable: mRS 0 to 2 versus 3 to 6
  3. bDependent variable: six mRS levels by collapsing mRS 5 and mRS 6 into a single level
  4. cAdjusted for age, sex, body mass index, diastolic blood pressure, hemoglobin, total cholesterol, LDL cholesterol, pre-stroke modified Rankin scale score, history of hypertension, diabetes mellitus, hyperlipidemia, atrial fibrillation, history of stroke, history of coronary artery disease, smoking, prior medication of any antiplatelet, anticoagulant, angiotensin receptor blocker or angiotensin converting enzyme inhibitor, beta-blocker, diuretics, calcium-channel blocker, TOAST classification, onset to arrival time, statin use during hospitalization, SYSO, and initial NIHSS score
  5. dPS-matched sample included 618 pairs with one-to-n (n ranged from one to four) matching: 618statin users and 1585 non-users
  6. eAdjusted for history of stroke, hyperlipidemia, total cholesterol, LDL cholesterol, prior medication of any antiplatelet, ARB + ACEI, statin use during hospitalization, SYSO, and initial NIHSS score
  7. fAdjusted for statin use during hospitalization, SYSO, and initial NIHSS score