Table 2 Comparison of cognitive and neuropsychiatric data between the two study groups
From: Neurocognitive functions and brain atrophy after proven neuroborreliosis: a case-control study
Parameter | Control group (n=30) | NB group (n=60) | p (univariate) | p (multivariate) |
|---|---|---|---|---|
State-trait Anxiety Inventory | 31.7±4.5 | 33.7±6.3 | 0.0761 | - |
(STAI) State (X1) | 31.0 (22.0–44.0) | 33.4 (21.0–53.0) | ||
State-trait Anxiety Inventory (STAI) Trait (X2) | 31.2 ±6.8 | 35.3 ±10.6 | 0.0345 | n.s. |
30.0 (21.0–49.9) | 32.0 (20.0–67.0) | |||
Hamilton Depression Scale | 4.6 ±5.9 | 8.6 ±8.0 | 0.010 | n.s. |
3.0 (0.0–20.0) | 6.0 (0.0–28.0) | |||
HADS A | 3.1 ±2.8 | 3.1 ±2.8 | 0.0190 | n.s. |
3.0 (0.0–11.0) | 4.0 (0.0–15.0) | |||
HADS D | 2.4±3.3 | 3.9±3.8 | 0.0737 | - |
1.0 (0.0–12.0) | 3.0 (0.0–15.0) | |||
Sleep quality (PSQI) | 4.8±3.6 | 4.5±3.0 | 0.7454 | - |
4.5 (0.0–14.0) | 4.0 (0.0–15.0) | |||
Diener’s Quality of Life Score | 20.4±3.5 | 19.2±4.3 | 0.1919 | - |
20.0 (9.0–25.0) | 20.0 (8.0–25.0) | |||
Quality of Life Bar | 7.4±2.2 | 6.4±2.2 | 0.0615 | - |
8.1 (1.9–10.0) | 7.0 (1.1–9.7) | |||
Nottingham Activities of Daily Living (NADL) | 87.8 ±1.3 | 86.8 ±2.1 | 0.0135 | n.s. |
88.0 (81.0–88.0) | 88.0 (81.0–88.0) | |||
Beck’s Depression Index (BDI) | 3.1±3.6 | 4.9±6.5 | 0.1087 | - |
2.0 (0.0–15.0) | 2.0 (0.0–15.0) | |||
Fibromyalgia Impact Questionnaire (FIQ) | 6.2 ±7.2 | 17.9 ±19.8 | 0.0001 | n.s. |
3.2 (0.0–35.0) | 10.4 (0.0–78.6) | |||
Working memory | −0.09±0.55 | −0.27±0.56 | 0.1525 | - |
−0.01 (−1.54–0.85) | −0.26 (−1.38–1.08) | |||
Verbal memory | −0.11±0.58 | −0.37±0.67 | 0.0603 | - |
−0.07 (−1.47–0.83) | −0.27 (−1.83–0.88) | |||
Non-verbal memory | 0.08±0.61 | −0.13±0.50 | 0.1037 | - |
0.23 (−1.61–1.34) | −0.10 (−1.36–0.84) | |||
Visuo-constructive functions | 0.62±0.59 | 0.42±0.78 | 0.1771 | - |
0.62 (−0.44 –1.72) | 0.57 (−1.77–1.81) | |||
Frontal executive functions | 0.09 ±0.60 | −0.29 ±0.60 | 0.0059 | 0.0161 |
0.21 (−1.43–1.19) | −0.22 (−1.62–1.04) | |||
Alertness | −0.17±0.39 | −0.23±0.45 | 0.5427 | - |
−0.16 (−1.16–0.68) | −0.21 (−1.23–0.75) | - | ||
Cognitive sum score | 0.08 ±0.31 | −0.15 ±0.42 | 0.0079 | 0.01 |
0.1 (−0.66–0.78) | −0.12 (−1.03–0.93) | |||
SCL 90r GSI | 41.3±11.8 | 46.6±14.9 | 0.0772 | - |
42.0 (21.0–74.0) | 45.0 (23.0–75.0) | |||
SCL 90r PST | 40.9±11.3 | 45.8±14.3 | 0.0852 | - |
41.0 (21.0–74.0) | 44.0 (23.0–79.0) | |||
Global sum score | 0.7 ±0.30 | −0.15 ±0.42 | 0.0083 | - |
0.10 (−0.66–0.78) | −0.12 (−1.03–0.93) |