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Table 3 Study flowchart of the HEBRAS study

From: HEart and BRain interfaces in Acute ischemic Stroke (HEBRAS) – rationale and design of a prospective oberservational cohort study

 

In-hospital stay

Follow-up

 

Admission

Day 1

Day ≥2

Discharge

3 months

12 months

Baseline data*

X

     

Past medical history

X

   

X

X

Heart rate at rest (routine)

X

X

Daily

X

  

Heart rhythm (routine)

X

X

Daily

X

  

12-lead ECG

X

     

24-hour Holter

  

(X)

   

Additional ECG monitoringa

ongoing

ongoingc

  

Respiratory rate

X

X

Daily

   

Clinical signs of infection

X

 

X

X

  

Leukocytes [per mm3]

X

     

Creatinine [mg/dl]

X

     

Potassium [mmol/l]

X

     

Serum hs troponin I [ng/l]

X

X

    

NT-proBNP [ng/l]

 

X

    

Urine norepinephrine [nmol/l]

 

X

    

Cardiac MRI

 

X

    

MR angiographyb

 

X

    

Brain MRI

 

X

    

NIHSS

X

  

X

  

Modified Rankin scale score

X

  

X

X

X

Recurrent stroke, myocardial infarction or death of any cause

 

X

X

X

 
  1. asee Methods section for more details
  2. bincluding the aortic arc and brain supplying arteries
  3. cextended for up to 5 days after hospital discharge/ transfer to a rehabilitation clinic