Fig. 2

Differential gene expression of RRMS IFN responders compared to untreated RRMS. a. Volcano plot - Each dot represents a gene, red dots demonstrate positive fold change and blue negative fold change. Cut off line showing p-value level of 0.05 by Bonferroni multiple correction, with 104 DEG’s above cut off line. b. Enrichment of IFN signaling pathway within RRMS IFN responders. Up-regulated genes are marked in red