|
Demographics
|
Total number
|
FD: R227Q
|
D313Y
|
|---|
|
Patients
|
178
|
1
|
1
|
|
Men
|
73 (40,7 %)
|
1
|
0
|
|
Age at recruitment
|
48,4a
|
41
|
52
|
|
Age at onset (symptomatic)
|
43,3a
| |
48
|
|
Age at onset (WMLs)
|
43,5a
|
41
| |
|
Risk factors
| | | |
|
Hypertension
|
106 (59,5 %)
|
1
|
1
|
|
Diabetes
|
11 (6,1 %)
|
0
|
0
|
|
Atrial fibrillation
|
3 (1,7 %)
|
0
|
0
|
|
Dyslipidemia
|
83 (46,6 %)
|
0
|
1
|
|
Smoking
|
40 (22,4 %)
|
0
|
0
|
|
Drinking habit
|
13 (7,3 %)
|
0
|
0
|
|
Oral contraception
|
5 (4,7 %)
|
NA
|
0
|
|
Hyperhomocysteine
|
22 (12,3 %)
|
1
|
1
|
|
Overweight/obesity
|
68 (38,2 %)
|
0
|
1
|
|
Fabry feature
| | | |
|
Acroparesthesia
|
13 (7,3 %)
|
1
|
0
|
|
Angiokeratoma
|
0
|
0
|
0
|
|
Cornea verticillata
|
1 (0,5 %)
|
0
|
0
|
|
CKD/Proteinuria
|
22 (12,3 %)
|
0
|
1
|
|
Cardiac involvement
|
32 (17,97 %)
|
1
|
1
|
-
Abbreviations: FD Fabry’s disease, NA not applicable, amedian NB cornea verticillata was associated with amiodarone
