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Table 1 Demographics and risk factors in patients and probands

From: Exploratory screening for Fabry’s disease in young adults with cerebrovascular disorders in northern Sardinia

Demographics Total number FD: R227Q D313Y
Patients 178 1 1
Men 73 (40,7 %) 1 0
Age at recruitment 48,4a 41 52
Age at onset (symptomatic) 43,3a   48
Age at onset (WMLs) 43,5a 41  
Risk factors    
 Hypertension 106 (59,5 %) 1 1
 Diabetes 11 (6,1 %) 0 0
 Atrial fibrillation 3 (1,7 %) 0 0
 Dyslipidemia 83 (46,6 %) 0 1
 Smoking 40 (22,4 %) 0 0
 Drinking habit 13 (7,3 %) 0 0
 Oral contraception 5 (4,7 %) NA 0
 Hyperhomocysteine 22 (12,3 %) 1 1
 Overweight/obesity 68 (38,2 %) 0 1
Fabry feature    
 Acroparesthesia 13 (7,3 %) 1 0
 Angiokeratoma 0 0 0
 Cornea verticillata 1 (0,5 %) 0 0
 CKD/Proteinuria 22 (12,3 %) 0 1
 Cardiac involvement 32 (17,97 %) 1 1
  1. Abbreviations: FD Fabry’s disease, NA not applicable, amedian NB cornea verticillata was associated with amiodarone