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Table 1 Differential diagnosis of chronic myelopathy (Intramedullary) based on MRI

From: Late-onset spinal form xanthomatosis without brain lesion: a case report

Immune-mediated Behcet’s disease
Mixed connective tissue disease
Multiple sclerosis
Neuro-sarcoidosis
Paraneoplastic
Sjogren disease
Solitary sclerosis
Systemic lupus erythematosus
Infectious Cysticercosis
Echinococcosis
Fungal
HTLV
HIV/AIDS
Schistosomiasis
Syphilis
Tuberculosis
Whipple’s disease
Vascular Cavernous malformation
Spinal arteriovenous malformation
Congenital Arachnoid cyst
Epidermoid cyst
Hypomyelination with brain stem and spinal cord involvement and leg spasticity
Spinal xanthomatosis
Toxic/metabolic Copper deficiency
Folic acid
Heroin
Konzo (cassava)
Neurolathyrism
Nitrous oxide toxicity
Radiation-induced
Vitamin B12 deficiency
Vitamin E deficiency toxicity
Degenerative Post-traumatic
Spondylotic myelopathy
Tumor/neoplasm Astrocytoma
Ependymoma
Hemangioblastoma
Intravascular lymphoma
Metastases
Schwannoma
Spinal lymphoma
Other Syringomyelia