COPPADIS-2015 (COhort of Patients with PArkinson’s DIsease in Spain, 2015), a global –clinical evaluations, serum biomarkers, genetic studies and neuroimaging– prospective, multicenter, non-interventional, long-term study on Parkinson’s disease progression

Table 3 Working Plan Summary

Assessments	Baseline	12 m	24 m	36 m	48 m	60 m
Inclusion/exclusion criteria	P; C
Hoehn & Yahr	P	P	P	P	P	P
UPDRS-III and UPDRS-IV	P	P	P	P	P	P
MMSE	P; C		P; C		P; C	P; C
PD-CRS	P; C		P; C		P; C	P; C
Puzzle test	P; C		P; C		P; C	P; C
NMSS	P; C	P	P; C	P	P; C	P; C
BDI-II	P; pC; C		P; pC; C		P; pC; C	P; pC; C
QUIP-RS	P; C		P; C		P; C	P; C
PDSS	P; C		P; C		P; C	P; C
NPI	P; C		P; C		P; C	P; C
VAS-Pain and VAFS	P; C		P; C		P; C	P; C
FOGQ	P; C		P; C		P; C	P; C
ADLS	P; C	P	P; C	P	P; C	P; C
PDQ-39SI	P; C		P; C		P; C	P; C
PQ-10	P; pC; C		P; pC; C		P; pC; C	P; pC; C
EUROHIS-QOL 8 item index	P; pC; C		P; pC; C		P; pC; C	P; pC; C
ZCBI	pC		pC		pC	pC
CSI	pC		pC		pC	pC
Samples-serum markers	P; C					P; C
Samples-genetic studies	P; C
Head MRI	P; C					P; C

ADLS Schwab & England activities of daily living scale, BDI beck depression inventory, C control, CSI caregiver strain index, EUROHIS-QOL European health interview survey-quality of life, FOGQ freezing of gait questionnaire, m month, MMSE mini mental state examination, MRI magnetic resonance imaging, NMSS non-motor symptoms scale, NPI neuropsychiatric inventory, P patient, pC primary caregiver, PD-CRS parkinson’s disease cognitive rating scale, PDQ-39SI 39-item parkinson’s disease quality of life questionnaire summary index, PDSS parkinson’s disease sleep scale, QUIP-RS questionnaire for impulsive-compulsive disorders in parkinson’s disease-rating scale, UPDRS unified parkinson’s disease rating scale, VAFS visual analog fatigue scale, VAS-Pain visual analog scale-pain, ZCBI zarit caregiver burden inventory

ISSN: 1471-2377