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Table 2 Factors predicting occurrence of depressive symptoms (Models 1, 2) and mood symptoms (Models 3, 4)

From: Variations in and predictors of the occurrence of depressive symptoms and mood symptoms in multiple sclerosis: a longitudinal two-year study

Dependent Variable

Independent variable categorisation

Model 1 and 3

OR (CI)a

n = 199b

P-value

Model 2 and 4

OR (CI) a

n = 183c

P-value

Depressive symptomsd

Weak coping capacity

Moderate/Strong

5.18 (2.64–10.10)

1

<0.001

4.90 (2.57–9.35)

1

<0.001

 

Reduced frequency of social/lifestyle activities

Normal frequency

2.20 (1.28–3.77)

1

0.004

Not significant in this group

 
 

Not working

Working

Not applicable

 

2.50 (1.43–4.35)

1

0.001

 

High psychological impact of MS/Time:

    

24 months

Baseline

3.94 (1.25–12.35)

1

0.019

5.78 (1.61–20.83)

1

0.007

 

12 months

Baseline

3.34 (1.02–10.99)

1

0.047

3.89 (1.07–14.29)

1

0.040

Mood symptomse

Weak coping capacity

Moderate/Strong

6.06 (3.05–12.05)

1

<0.001

5.81 (3.08–11.11)

1

<0.001

 

Reduced frequency of social/lifestyle activities

Normal frequency

2.29 (1.25–4.22)

1

0.008

Not significant in this group

 
 

Not working

Working

Not applicable

 

1.93 (1.04–3.60)

1

0.037

 

High physical impact of MS

Low impact

Not significant in this group

 

2.27 (1.02–5.05)

1

0.044

 

High psychological impact of MS/Time:

    

24 months

Baseline

5.85 (1.04–33.33)

1

0.046

6.37 (1.10–37.04)

1

0.038

 

12 months

Baseline

3.91 (0.83–18.52)

1

0.084

3.79 (0.80–17.86)

1

0.093

  1. a Estimated odds ratios (OR), 95 % confidence intervals (CI) and p values for the predictive value of the selected factors
  2. bModel 1 and 3: n = 199 – all PwMS were included, these models included all the independent variables except work status
  3. cModel 2 and 4: n = 183 – PwMS < 65 years of age were included, these models included all the independent variables
  4. dBDI Total: The Beck Depression Inventory
  5. eBDI Mood: The mood cluster in the Beck Depression Inventory