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Table 2 Correlation of change from baseline to day 90/final visit in CNS-LS score with other outcome measures—effectiveness analysis Set

From: PRISM II: an open-label study to assess effectiveness of dextromethorphan/quinidine for pseudobulbar affect in patients with dementia, stroke or traumatic brain injury

Variable

Pearson Correlation

P value

Weekly PBA episode rate change

0.21

<.001

QOL-VAS change

0.40

<.001

PGI-C

0.47

<.001

CGI-C

0.48

<.001

PHQ-9 change

0.32

<.001

Patient satisfaction score

−0.22

<.001

MMSE change

0.01

.877

  1. CGI-C clinical global impression of changes, CNS-LS Center for neurologic study—lability scale, MMSE mini-mental state exam, PBA pseudobulbar affect, PGI-C patient/caregiver global impression of change, PHQ-9 9-item patient health questionnaire, QOL-VAS quality-of-life visual analog scale
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BMC Neurology

ISSN: 1471-2377

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