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Table 2 Correlation of change from baseline to day 90/final visit in CNS-LS score with other outcome measures—effectiveness analysis Set

From: PRISM II: an open-label study to assess effectiveness of dextromethorphan/quinidine for pseudobulbar affect in patients with dementia, stroke or traumatic brain injury

Variable Pearson Correlation P value
Weekly PBA episode rate change 0.21 <.001
QOL-VAS change 0.40 <.001
PGI-C 0.47 <.001
CGI-C 0.48 <.001
PHQ-9 change 0.32 <.001
Patient satisfaction score −0.22 <.001
MMSE change 0.01 .877
  1. CGI-C clinical global impression of changes, CNS-LS Center for neurologic study—lability scale, MMSE mini-mental state exam, PBA pseudobulbar affect, PGI-C patient/caregiver global impression of change, PHQ-9 9-item patient health questionnaire, QOL-VAS quality-of-life visual analog scale