Fig. 4

Profiling patients and collecting data. As part of the personalized medicine approach, MS patients should be characterized by a detailed clinical profiling which is the base of all long-term documentation. All patients should be documented during the course of the disease to understand treatment response, document relapses and disease progression as well as quantitative inflammatory and neurodegenerative magnetic resonance imaging (MRI) markers. Physician- and patient-centered parameters should be collected by intelligent software systems as MSDS software. MS big data can be used to analyze treatment response patterns and allow personalized treatments. Therefore, the available information (big data MS) of all included MS patients can assist in complex treatment decisions in future