Fig. 2
From: Applied multimodal diagnostics in a case of presenile dementia
Positron emission tomography of the brain with F-18-labeled fluorodeoxyglucose (FDG-PET) and three-dimensional surface representation of brain regions with grey matter reduction of our 59-year-old AD patient compared to 18 healthy controls. Top: regional uptake of radiolabelled glucose; the left lateral, left medial and right lateral views of the brain are presented. Middle: regional metabolic reduction compared to age-matched healthy controls according to the methodology of Minoshima et al. [53]. There is an asymmetric metabolic reduction parietotemporal and in posterior cingulate cortex with a more pronounced reduction of glucose metabolism in the right hemisphere. Bottom: color-coded brain matter reduction. Z-values of grey matter reduction are projected on T1-weighted, averaged brain surface of healthy control subjects