Table 1 Baseline demographics and epilepsy characteristics (intent-to-treat population)
| Â | Overall | VPA stratum | CBZ stratum | |||
|---|---|---|---|---|---|---|
|  | LEV (n = 152) | Standard AEDs (n = 155) | LEV (n = 48) | VPA-ER (n = 52) | LEV (n = 104) | CBZ-CR (n = 103) |
Age, years, mean (SD) | 69.5 (6.2) | 69.7 (6.4) | 71.1 (6.8) | 70.4 (6.5) | 68.8 (5.9) | 69.3 (6.4) |
Gender, n (%) | ||||||
 Men | 85 (55.9) | 87 (56.1) | 25 (52.1) | 33 (63.5) | 60 (57.7) | 54 (52.4) |
 Women | 67 (44.1) | 68 (43.9) | 23 (47.9) | 19 (36.5) | 44 (42.3) | 49 (47.6) |
Number of seizures in the last 2 yearsa, median (Q1–Q3) [n] | 4 (2–6) [150] | 4 (2–8) [149] | 3 (2–6) [47] | 3 (2–5) [51] | 4 (2–8) [102] | 4 (3–10) [99] |
Epilepsy durationb, years, median (Q1–Q3) | 0.70 (0.27–2.95) | 0.70 (0.30–2.12) | 0.79 (0.20–2.24) | 0.73 (0.26–1.84) | 0.63 (0.28–3.15) | 0.70 (0.32–2.55) |
Seizure typec, n (%) | ||||||
 Simple focal | 30 (19.7) | 32 (20.6) | 5 (10.4) | 4 (7.7) | 25 (24.0) | 28 (27.2) |
 Complex focal | 62 (40.8) | 62 (40.0) | 15 (31.3) | 11 (21.2) | 47 (45.2) | 51 (49.5) |
 SG or tonic clonic | 84 (55.3) | 89 (57.4) | 30 (62.5) | 38 (73.1) | 54 (51.9) | 51 (49.5) |
 Otherd | 4 (2.6) | 4 (2.6) | 3 (6.3) | 3 (5.8) | 1 (1.0) | 1 (1.0) |
 Unclassifiede | 5 (3.3) | 3 (1.9) | 4 (8.3) | 3 (5.8) | 1 (1.0) | 0 |