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Table 4 Association between SNPs and SVD using the additive, genotype, dominant, and the recessive models

From: Association study of polymorphisms in the ABO gene with ischemic stroke in the Chinese population

SNP

Model

Allele or geno

case

control

Unadjusted OR (95 % CI)

Unadjusted

p-value

Adjusted

OR (95 % CI)

Adjusted p-value

rs579459

Additive

C/T

166/734

334/1576

1.07 (0.87-1.31)

0.54

1.08 (0.85-1.39)

0.53

 

Dominant

CC + CT/TT

152/298

300/655

1.11 (0.88-1.41)

0.38

1.10 (0.83-1.47)

0.51

 

Recessive

CC/CT + TT

14/436

34/921

0.87 (0.46-1.64)

0.67

1.09 (0.51-2.32)

0.83

rs651007

Additive

T/C

156/718

337/1575

1.02 (0.82-1.25)

0.89

1.03 (0.80-1.33)

0.80

 

Dominant

TT + CT/CC

144/293

304/652

1.05 (0.83-1.34)

0.67

1.04 (0.78-1.39)

0.81

 

Recessive

TT/CT + CC

12/425

33/923

0.79 (0.40-1.54)

0.49

1.05 (0.47-2.32)

0.91

rs529565

Additive

C/T

305/569

709/1201

0.91 (0.77-1.07)

0.26

0.94 (0.77-1.14)

0.51

 

Dominant

CC + CT/TT

245/192

565/390

0.88 (0.70-1.11)

0.28

0.87 (0.66-1.15)

0.33

 

Recessive

CC/CT + TT

60/377

144/811

0.90 (0.65-1.24)

0.51

1.01 (0.69-1.50)

0.95

  1. All SNPs were analyzed under additive, genotype, dominant (Dom) and recessive (Rec) models; OR: odds ratio; CI: confidence interval; unadjusted P-value from t-test; adjusted P-value using logistic regression analysis with age, gender, hypertension, diabetes, and dyslipidemia as covariates. Significant P values (p < 0.05) are in bold and p* < 0.017 (Bonferroni multiple correction threshold)