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Fig. 3 | BMC Neurology

Fig. 3

From: Chloroquine, an autophagy inhibitor, potentiates the radiosensitivity of glioma initiating cells by inhibiting autophagy and activating apoptosis

Fig. 3

Irradiation obviously promoted autophagy and obviously enhanced autophagy associated proteins expression in U87 GICs, and chloroquine can significantly inhibit the autophagy process which induced by radiation. a Representative images(×200) of the indicated regions of U87 GICs, which analyzed for LC3 expression by immunofluorescence analysis. b Quantitative analysis of the number of cells with punctuate GFP-LC3. c Authophagy-associated protein LC3 level in U87 GICs were examined by Western blotting. d Quantification of LC3 protein expression in U87 GICs treated by indicated treatments after normalization with GAPDH levels. Mean ± SD. n = 3. (*, p < 0.05;**p < 0.01)

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BMC Neurology

ISSN: 1471-2377

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