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Fig. 3 | BMC Neurology

Fig. 3

From: Non-neuronal cholinergic activity is potentiated in myasthenia gravis

Fig. 3

PBMC-derived ACh is positively associated with anti-MuSK Ab concentrations. a No correlation was found between ACh levels and anti-AChR antibodies (n = 40) (p = 0.1673). b A positive correlation was found between ACh levels and anti-MuSK antibodies (n = 15) (p < 0.0001 by regression analysis). c Histogram shows that anti-MuSK Ab concentrations relative to MG severity (n = 3 for class I and II, n = 4 for class III, n = 5 for class IV-V) (p = 0.0135 by Kruskal-Wallis). d Anti-MuSK Ab distributions in relation to QMG scores (n = 15) (p = 0.0046 by regression analysis). e The ACh levels were higher in anti-MuSK Ab-positive group than that in double-negative and anti-AChR Ab-positive groups (n = 24 in double-negative group, n = 86 in anti-AChR Ab-positive group, n = 15 in anti-MuSK Ab-positive group) (p < 0.001, p < 0.01, respectively)

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