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Fig. 2 | BMC Neurology

Fig. 2

From: Looking beyond the brain to improve the pathogenic understanding of Parkinson’s disease: implications of whole transcriptome profiling of Patients’ skin

Fig. 2

A schematic presentation of the manifestation of Parkinson’s Disease in skin, as characterized by an interplay of alterations affecting six central molecular processes, leading to basal cellular stress and homeostatic imbalance. These processes can be considered as the reflection of Parkinson’s Disease pathology in skin, but in the setting of internal and external mutagenic hazards, these alterations can also form the underlying basis for increased risk of skin cancers in these patients

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