Table 4 List of clinical sensory and vestibular tests for classification and covariates / comorbidities of primary and secondary outcomes
Domain Tested | Test | Description | Positive Result |
|---|---|---|---|
Sensory | Proprioception test | Assess the ability of the participant to detect the position of the great toe or ankle as it is moved by a researcher / clinician | Unable to detect changes in position |
|  | Visual Vertical Test | Requires participant to orient a line to vertical and quantifies the deviation from vertical | Falls outside control group mean ± 2 SD |
Ocular Motor | Saccadic Latency | Assesses the ability to make a rapid eye movement, latency would be the time it takes to initiate a saccade (eye movement) after the target has moved | Falls outside control group mean ± 2 SD |
| Â | Gaze | Assesses the ability to maintain stable vision on a fixed target. | |
| Â | Smooth Pursuit | Assesses the ability to accurately track/follow a moving/sinusoidal target with the eyes. | |
| Â | Convergence | Assesses the ability to view a close target without double vision | |
Vestibular | cVEMP | Neurophysiological test assessing the function of the saccule | Falls outside control group mean ± 2 SD |
| Â | oVEMP | Neurophysiological test assessing the function of the utricle | |
| Â | Caloric | Assesses function of the lateral semi-circular canals and superior branch of the vestibular nerves | |
| Â | Head Impulse | Assesses function of semi-circular canals and vestibular nerve branches, specifically the lateral canals/superior vestibular nerve |