Table 1 Baseline characteristics of patients with infratentorial or cervical spinal cord demyelinating lesions in comparison to healthy control subjects
From: Finger tapping impairments are highly sensitive for evaluating upper motor neuron lesions
Baseline characteristics | Patients (N = 23) | Healthy controls (N = 12) | P value |
|---|---|---|---|
Sex, N(%) | |||
Male | 6 (26%) | 8 (67%) | 0.31a |
Female | 17 (74%) | 4 (33%) | |
Age (years) | |||
Mean (SD) | 44.8 (14.6) | 37.4 (14.5) | 0.87b |
Range | 22 – 74 | 22 – 62 | |
Ethnicity, N(%) | |||
White | 22 (96%) | 11 (92%) | 0.57a |
African American | 1 (4%) | 0 (0%) | |
Middle Eastern | 0 (0%) | 1 (8%) | |
Handedness, N(%) | |||
Right | 21 (91%) | 11 (92%) | 0.73a |
Left | 2 (9%) | 1 (8%) | |
Disease subtype, N(%) | |||
CIS | 4 | ||
RRMS | 17 | ||
SPMS | 1 | ||
PPMS | 1 | - | - |
Age at onset of disease symptoms (years) | |||
Mean (SD) | 36.5 (14.7) | - | - |
Range | 16 – 68 | ||
Disease duration from onset of symptoms (years) | |||
Mean (SD) | 8.7 (9.1) | - | - |
Range | 0 – 39 | ||
Lesion location on MRI, Nc | |||
Infra-tentorial | 20 | - | - |
Brainstem | 15 | ||
Cerebellum | 18 | ||
Cervical spinal cord | 18 | ||