NPRS ‘average pain’ scores | PHN (n = 89) | HIV-AN (n = 5) | NBP (n = 50) | CRNP (n = 22) | PONP (n = 198) | Other (n = 56) | Overall (n = 420) |
---|---|---|---|---|---|---|---|
First treatment | |||||||
 Baseline, mean (95% CI) | 7.1 (6.9, 7.5) n = 88 | 6.4 (5.1, 7.7) n = 5 | 7.3 (6.8, 7.9) n = 50 | 7.2 (6.6, 7.8) n = 22 | 6.8 (6.6, 7.1) n = 198 | 6.9 (6.4, 7.4) n = 56 | 6.9 (6.7, 7.1) n = 419 |
 Weeks 2 and 8, mean (95% CI) | 4.9 (4.4, 5.4) n = 89 | 4.6 (2.0, 7.3) n = 4 | 4.8 (4.2, 5.5) n = 48 | 5.8 (4.9, 6.7) n = 21 | 5.2 (4.9, 5.5) n = 195 | 4.5 (4.0, 5.1) n = 56 | 5.0 (4.8, 5.2) n = 412 |
 Percentage reduction, mean (95% CI) | 29.7 (23.4, 36.0) | 34.5 (7.6, 61.5) | 30.9 (21.7, 40.1) | 21.0 (11.6, 30.5) | 22.3 (17.7, 27.0) | 34.3 (27.3, 41.4) | 26.6 (23.6, 29.6) |
Second treatment | |||||||
 Baseline, mean (95% CI) | 7.1 (6.5, 7.7) n = 39 | 6.5 (3.6, 9.4) n = 2 | 7.7 (6.7, 8.7) n = 15 | 6.9 (5.9, 7.9) n = 8 | 6.8 (6.4, 7.2) n = 97 | 6.6 (5.7, 7.5) n = 19 | 6.9 (6.6, 7.2) n = 180 |
 Weeks 2 and 12, mean (95% CI) | 4.7 (4.1, 5.3) n = 39 | 3 (–) n = 2 | 4.3 (2.8, 5.8) n = 12 | 3.4 (1.6, 5.2) n = 6 | 4.9 (4.4, 5.4) n = 85 | 5.1 (4.1, 6.1) n = 18 | 4.8 (4.5, 5.1) n = 162 |
 Percentage reduction, mean (95% CI) | 30.5 (19.8, 41.2) n = 38 | 51.3 (29.2, 73.4) n = 2 | 44.9 (24.7, 65.1) n = 12 | 51.0 (24.3, 77.7) n = 6 | 25.0 (16.5, 33.5) n = 85 | 21.4 (5.2, 37.6) n = 18 | 28.7 (22.9, 34.5) n = 161 |
Third treatment | |||||||
 Baseline, mean (95% CI) | 6.9 (5.9, 7.9) n = 16 | – | 7.5 (4.6, 10.4) n = 4 | 7.8 (6.3, 9.3) n = 4 | 6.3 (5.8, 6.8) n = 38 | 6.8 (5.6, 8.0) n = 8 | 6.7 (6.3, 7.1) n = 70 |
 Weeks 2 and 12, mean (95% CI) | 3.9 (2.9, 4.9) n = 14 | – | 5.5 (3.5, 7.5) n = 4 | 5.0 (2.6, 7.4) n = 4 | 4.4 (3.7, 5.1) n = 29 | 5.2 (4.2, 6.2) n = 8 | 4.5 (4.0, 5.0) n = 59 |
 Percentage reduction, mean (95% CI) | 42.3 (26.8, 57.8) n = 14 | – | 25.4 (15.3, 35.5) n = 4 | 35.5 (8.8, 62.2) n = 4 | 23.1 (9.5, 36.7) n = 29 | 13.6 (–20.8, 48.0) n = 8 | 27.3 (18.1, 36.5) n = 59 |