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Table 4 The linear- regression between multiple variables and ARR improvements (in log)

From: Relationship between Azathioprine metabolites and therapeutic efficacy in Chinese patients with neuromyelitis optica spectrum disorders

Variable Standardized coefficients- Beta T P-value
Constant (SE) 0.417 (0.116) 3.580 0.002
Normalized Concentration of 6-TGNs −0.489 −2.689 0.013*
Excluded variables
 Age of onset, year 0.156 0.853 0.403
 Disease duration, months 0.094 0.509 0.616
 Treatment duration, months −0.200 −1.106 0.281
 Pre-therapy EDSS score 0.034 0.176 0.862
 Post-therapy EDSS score 0.050 0.266 0.793
 Mean CSF protein, mg/dl −0.038 −0.198 0.845
 Mean Concentration of CSF IgG, mg/ml −0.158 −0.855 0.402
 CSF IgG index (n%) −0.287 −1.636 0.116
 Normalized Concentration of MMPNs −0.150 −0.751 0.461
  1. NMOSD, AZA Azathioprine, BMI Body mass index, ARR Annual relapse rate, EDSS Expanded disability status scale, 6-TGN 6-thioguanine nucleotides, 6-MMPN 6-methylmercaptopurine nucleotides. All P-value <0.05 was considered statistically significant