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Fig. 2 | BMC Neurology

Fig. 2

From: Nasal administration of the neuroprotective candidate NeuroEPO to healthy volunteers: a randomized, parallel, open-label safety study

Fig. 2

Hematological parameters before and after treatment with NeuroEPO. Data correspond to the healthy subjects who received 1 mg of NeuroEPO (Group A, N = 12) or 0.5 mg of NeuroEPO (Group B, N = 13) every 8 h, during 4 days, by nasal route. Points correspond to median and deviations for each measure before treatment (day 0) and after it (day 5, day 14). a Reticulocytes count (0.5–1.5%). b Hemoglobin (M: 130–175 g/L; W: 120–165 g/L). c Hematocrit (M: 0.41–0.54; W: 0.37–0.47). Post-treatment vs. initial analysis (Wilcoxon’s test) is showed for the three variables. Differences between groups of treatment were no significant at each time (p > 0.05, Mann-Whitney’s U test)

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