Table 1 Baseline and treatment characteristics
All patients (n = 40) | Low temperature load patients (n = 20) | High temperature load patients (n = 20) | p value | |
|---|---|---|---|---|
Age, years, mean (SD) | 58.9 ± 10.1 | 59.0 ± 10.6 | 58.9 ± 9.9 | 0.976 |
Sex (female), n (%) | 19 (47.5) | 10 (50.0) | 9 (45.0) | >0.99 |
Arterial hypertension, n (%) | 25 [62.5] | 13 [65) | 12 [60] | >0.99 |
Hyperlipidemia, n (%) | 11 [27.5] | 7 [35] | 4 [20] | 0.480 |
Diabetes mellitus, n (%) | 14 [35] | 7 [35] | 7 [35] | 1.0 |
Atrial fibrillation, n (%) | 10 [25] | 5 [25] | 5 [25] | 1.0 |
Transfer from rural hospital to stroke center, n (%) | 30 [75] | 16 [80] | 14 [70] | 0.716 |
NIHSS score (admission), median (IQR) | 32 [20–32] | 28 (20.25–32) | 32 (18–32) | 0.695 |
Dominant hemisphere, n (%) | 22 (55.0) | 14 (70.0) | 8 (40.0) | 0.111 |
Intravenous rtPA, n (%) | 20 [50] | 7 [35] | 13 [65] | 0.113 |
Endovascular therapy, n (%) | 8 [20] | 2 [10] | 6 [30] | 0.235 |
Symptom onset to hemicraniectomy, h, mean (SD) | 30.5 (16.7) | 31.6 (22.2) | 29.4 (10.3) | 0.695 |
Diameter of hemicraniectomy, cm, median (IQR) | 12.9 (12.1–13.4) | 13.0 (12.1–13.5] | 12.8 (12.0–13.3) | 0.867 |
Period of 96 h after surgery | ||||
Leucocytosis, n (%) | 36 (90) | 17 (85) | 19 (95) | 0.605 |
Antibiotics, n (%) | 40 (100) | 20 (100) | 20 (100) | NA |
Antipyretics, n (%) | 35 (87.5) | 15 (75) | 20 (100) | 0.024 |
One antipyretic, n (%) | 15 (37.5) | 8 (40) | 7 (35) | |
Two antipyretics, n (%) | 20 (50) | 7 (35) | 13 (65) | |
Acetaminophen, g, mean (SD) | 2.95 (2.2) | 2.4 (2.5) | 3.5 (1.8) | 0.044 |
Metamizole, g, mean (SD) | 1.38 (1.9) | 1.05 (1.85) | 1.7 (2) | 0.132 |
Temperature load 96 h, >36.5 °C; °C x h, mean (SD) | 62.3 (47.6) | 20 (19.2) | 104.6 (22.4) | < 0.001 |
Temperature load 96 h, >37.5 °C; °C x h, mean (SD) | 14.3 (15.4) | 3.8 (7.3) | 24.68 (14.4) | < 0.001 |
Patients with T > 37.5 °C, n (%) | 26 (65) | 12 (60) | 14 (70) | 0.741 |