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Table 1 Characteristics of the patients

From: Right-to-left shunt and subclinical ischemic brain lesions in Chinese migraineurs: a multicentre MRI study

Characteristics

RLS

No RLS

P value

(n = 224)

(n = 110)

Demographics

 Age (mean ± SD, years)

42.49 ± 10.97

44.03 ± 10.12

0.147

 Female

160 (71.4)

81 (73.6)

0.672*

The main risk factors of vascular disease

 BMI (mean ± SD)

22.98 ± 3.32

20.03 ± 3.61

0.281

 Hypertension

25 (11.2)

15 (13.6)

0.513*

 Diabetes

5 (2.2)

5 (4.5)

0.244*

 Heart disease

6 (2.7)

4 (3.6)

0.629*

 Smoking

  

0.627*

  Never

189 (84.4)

97 (88.2)

 

  Current

23 (10.3)

8 (7.3)

 

  Former

12 (5.4)

5 (4.5)

 

Headache characteristics

 Aura

67 (29.9)

19 (17.3)

0.013*

 Family history of headache

65 (29.0)

26 (23.6)

0.299*

 Age of onset

31.01 ± 11.85

32.65 ± 11.92

0.776

 Years from the first attack

11.84 ± 11.16

11.39 ± 10.45

0.731

MRI Findings

   

0.265*

 SBI

20 (8.9)

6 (5.5)

 
   

0.066

  Posterior circulation only

10 (4.5)

1 (0.9)

0.166*

  Single silent brain infarct

12 (5.4)

4 (3.6)

 
   

0.355*

 WMHs

122 (54.5)

54 (49.1)

 
   

0.543

  pvWMHs

7 (3.1)

2 (1.8)

 

  dWMHs

94 (42.0)

46 (41.8)

0.980*

  dWMHs and pvWMHs

21 (9.4)

6 (5.5)

 
  1. Abbreviations: BMI body mass index, MRI magnetic resonance imaging, SBI silent brain infarctions, WMHs white matter hyperintensities, pvWMHs periventricular WMHs, dWMHs deep WMHs
  2. Data are presented as n (%) unless otherwise specified
  3. *Pearson’s χ2, unadjusted for aura;
  4. unpaired t-test
  5. P for trend computed by binary logistic regression