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Table 1 Demographics and baseline characteristics of patients (N = 46)

From: Chronic kidney disease and poor outcomes in ischemic stroke: is impaired cerebral autoregulation the missing link?

Demographics

 

 Male, n (%)

19 (41)

 Age, years (mean ± SD)

73 ± 12

 BMI, Kg.m− 2 (mean ± SD)

27 ± 5

 Previous stroke/TIA, n (%)

6 (13)

 Hypertension, n (%)

28 (61)

 Diabetes Mellitus, n (%)

14 (30)

 Dyslipidemia, n (%)

27 (59)

 Tobacco, n (%)

4 (9)

 Previous MI, n (%)

2 (4)

 Atrial Fibrillation, n (%)

20 (43)

Chronic Medication, n (%)

 

 Antiplatelet

18 (39)

 Statin

17 (37)

 Beta-Blocker

10 (22)

 ACEI/ARB

15 (33)

 CCB

9 (20)

Stroke characteristics

 

 Etiology (TOAST), n (%)

 

  Large Vessel

6 (13)

  Cardioembolic

18 (39)

  Small vessel

2 (4)

  Other

1 (2)

  Undetermined

12 (26)

 Occlusion of affected MCA

16 (35)

 Baseline NIHSS score [median(IQR)]

14 (9–22)

Neuroimaging [median(IQR)]

 

 Infarct Volume, mL

19 (2–139)

 Leucoencephalopathy grade (VanSwieten scale [33])

2 (1–3)

Laboratorial (mean ± SD)

 

 Total cholesterol, mg/dL

174 ± 72

 LDL cholesterol, mg/dL

105 ± 42

 HDL cholesterol, mg/dL

46 ± 11

 Triglycerides, mg/dL

111 ± 68

 Glucose, mg/dL

140 ± 81

 HbA1C, %

6.4 ± 1.4

 Creatinine, mg/dL

1.0 ± 1.0

Renal Function

 

 eGFR, ml/min/1.73 m2

80 ± 39

  CDK–EPI Stage 0–1, n (%)

10 (22)

  CDK–EPI Stage 2, n (%)

23 (50)

  CDK–EPI Stage 3, n (%)

13 (28)

  CDK–EPI Stage 4, n (%)

1 (2)

  CDK–EPI Stage 5, n (%)

1 (2)

  1. Body-Mass Index (BMI), Transitory Ischemic Attack (TIA), angiotensin-conversion-enzyme inhibitor (ACEI), angiotensin receptor blocker (ARB), calcium channel blocker (CCB), Trial of ORG10172 in Acute Stroke Treatment (TOAST), middle cerebral artery (MCA), National Institutes of Health Stroke Scale (NIHSS), Low-density lipoprotein (LDL), High-density lipoprotein (LDL), glycated hemoglobin (HbA1C), eGFR (estimated glomerular filtration rate) by Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula [25]