Chronic kidney disease and poor outcomes in ischemic stroke: is impaired cerebral autoregulation the missing link?

Table 2 Systemic and cerebral hemodynamic characteristics of patients (N = 46)

Systemic hemodynamics (mean ± SD)
Systolic ABP, mmHg	144 ± 19
Mean ABP, mmHg	98 ± 11
Diastolic ABP, mmHg	75 ± 11
Heart rate, bpm	67 ± 11
LF mean ABP variability, mmHg²	85 ± 111
HF mean ABP variability, mmHg²	13 ± 20
EtCO₂, mmHg	36 ± 7
Cerebral hemodynamics (mean ± SD)
Ipsilateral
MFV, cm/s	40 ± 20
CVRi, mmHg/(cm/s)	2.3 ± 0.9
LF MFV variability, (cm/s)²	128 ± 142
HF MFV variability, (cm/s)²	35 ± 49
Contralateral
MFV, cm/s	48 ± 17
CVRi, mm Hg/(cm/s)	1.7 ± 0.7
LF MFV variability, (cm/s)²	200 ± 250
HF MFV variability, (cm/s)²	47 ± 68
Dynamic cerebral autoregulation
Ipsilateral
LF coherence, a.u.	0.5 ± 0.2
LF gain, %²/mmHg²	1.0 ± 0.3
LF phase, degrees	32 ± 23
HF coherence, a.u.	0.6 ± 0.2
HF gain, %²/mmHg²	1.5 ± 0.6
HF phase, degrees	– 0.1 ± 13
Contralateral
LF coherence, a.u.	0.5 ± 0.2
LF gain, %²/mmHg²	1.2 ± 0.5
LF phase, degrees	44 ± 26
HF coherence, a.u.	0.7 ± 0.2
HF gain, %²/mmHg²	1.5 ± 0.6
HF phase, degrees	– 0.7 ± 13

Arterial blood pressure (ABP), mean flow velocity (MFV), estimated cerebrovascular resistance (CVRi), end-tidal carbon dioxide (EtCO2), Low (LF: 0.3–0.15 Hz) and high (HF: 0.15–0.5 Hz) frequency spectral bands; a.u., arbitrary units

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