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Fig. 3 | BMC Neurology

Fig. 3

From: Comparison of electroencephalographic changes in response to acute electrical and thermal stimuli with the tail flick and hot plate test in rats administered with opiorphin

Fig. 3

Least square means for the tail immersion time (sec) at different time points. There was a significant increase in tail flick times at one and 5 min after an IV injection of morphine and 5 min after an injection of opiorphin. There was a significant decrease in tail flick times after an IV injection of naloxone. The control group did not receive an injection of naloxone. Note 1: Mean values with an asterisk over the error bars differed significantly (p < 0.05) from their respective baseline values. Note 2: Mean values with at least one common letter over the error bars, within the each time-point, did not differ significantly (p > 0.05). Note 3: Baseline = tail flick latency before the drug administration; 1 min after drug = tail flick latency 1 min after an i.v. injection of normal saline, opiorphin or morphine; 5 mins after drug = tail flick latency 5 min after an i.v. injection of normal saline, opiorphin or morphin; 5 mins Naloxone = tail flick latency 5 min after a s.c. injection of Naloxone

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BMC Neurology

ISSN: 1471-2377

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