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Table 4 Impact of 3-month ST and nST training on cognitive performances in POMS and ADHD groups

From: Computer-assisted rehabilitation of attention in pediatric multiple sclerosis and ADHD patients: a pilot trial

  ST nST p-value
Cognitive Test Baseline Post - Treatment Baseline Post - Treatment Effect for group × time
POMS
 SRT- LTS 29.9 (12.6) 35.4 (5.0) 24.6 (6.5) 28.9 (4.2) 0.72
 SRT - CLTR 22.1 (11.0) 27.3 (5.2) 20.4 (7.5) 22.6 (6.1)* 0.30
 SPART 19.3 (4.4) 25.5 (1.7)* 22.8 (2.0) 23.1 (1.9) 0.004
 SDMT 24.5 (4.6) 46.3 (6.7)* 20.5 (3.6) 20.8 (4.1) < 0.0001
 Trail Making Test A 39.4 (11.5) 31.8 (6.6) 34.6 (9.8) 43.8 (10.2) 0.01
 Trail Making Test B 108.4 (61.4) 70.5 (32.1) 107.9 (79.4) 64.0 (61.3) 0.87
 SRT-D 6.3 (2.8) 8.1 (0.8) 5.8 (1.5) 6.4 (0.7) 0.28
 SPART-D 6.8 (1.0) 8.1 (0.8)* 7.0 (1.4) 6.1 (0.8) 0.004
 Tower of London 15.8 (5.4) 30.4 (2.5)* 15.6 (6.6) 13.8 (2.0) < 0.0001
 Cognitive Impairment Index 22.5 (3.9) 10.4 (3.3)* 22.3 (2.4) 19.3 (2.2)* < 0.0001
ADHD
 SRT- LTS 32.2 (6.9) 34.9 (7.3) 29.6 (6.7) 30.5 (6.8) 0.50
 SRT - CLTR 25.5 (8.2) 27.3 (5.0) 18.3 (7.8) 22.6 (4.4) 0.51
 SPART 18.3 (4.9) 22.0 (4.2)* 21.2 (4.2) 21.2 (3.7) 0.06
 SDMT 17.1 (5.5) 35.8 (7.2)* 17.4 (11.1) 22.1 (11.4) 0.004
 Trail Making Test A 61.9 (17.3) 38.4 (22.2)* 46.1 (26.2) 31.5 (16.9) 0.51
 Trail Making Test B 160.8 (45.4) 108.7 (61.0)* 204.6 (75.9) 178.0 (131.11) 0.51
 SRT-D 7.1 (2.1) 6.8 (2.0) 6.2 (1.8) 6.6 (1.0) 0.41
 SPART-D 6.0 (2.2) 7.7 (2.0)* 6.9 (2.3) 6.6 (1.2) 0.04
 Tower of London 15.9 (9.1) 30.5 (11.0)* 13.5 (11.3) 17.9 (12.6) 0.27
 Cognitive Impairment Index 23.8 (4.7) 15.3 (5.6)* 23.4 (4.0) 19.3 (3.6)* 0.06
  1. Abbreviations: POMS pediatric onset multiple sclerosis, ADHD Attention Deficit Hyperactivity Disorder, ST specific training, nST non specific training, SRT-LTS Selective Reminding Test Long Term Storage, SRT-CTLR Selective Reminding Test Consistent Long-Term Retrieval, SRT-D Selective Reminding Test–Delayed, SPART Spatial Recall Test, SPART-D Spatial Recall Test–Delayed, SDMT Symbol Digit Modalities Test, CDI Children’s Depression Inventory
  2. *Indicate significant Effect for time (Baseline vs Post – Treatment comparison); p < 0.05