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Table 4 Impact of 3-month ST and nST training on cognitive performances in POMS and ADHD groups

From: Computer-assisted rehabilitation of attention in pediatric multiple sclerosis and ADHD patients: a pilot trial

 

ST

nST

p-value

Cognitive Test

Baseline

Post - Treatment

Baseline

Post - Treatment

Effect for group × time

POMS

 SRT- LTS

29.9 (12.6)

35.4 (5.0)

24.6 (6.5)

28.9 (4.2)

0.72

 SRT - CLTR

22.1 (11.0)

27.3 (5.2)

20.4 (7.5)

22.6 (6.1)*

0.30

 SPART

19.3 (4.4)

25.5 (1.7)*

22.8 (2.0)

23.1 (1.9)

0.004

 SDMT

24.5 (4.6)

46.3 (6.7)*

20.5 (3.6)

20.8 (4.1)

< 0.0001

 Trail Making Test A

39.4 (11.5)

31.8 (6.6)

34.6 (9.8)

43.8 (10.2)

0.01

 Trail Making Test B

108.4 (61.4)

70.5 (32.1)

107.9 (79.4)

64.0 (61.3)

0.87

 SRT-D

6.3 (2.8)

8.1 (0.8)

5.8 (1.5)

6.4 (0.7)

0.28

 SPART-D

6.8 (1.0)

8.1 (0.8)*

7.0 (1.4)

6.1 (0.8)

0.004

 Tower of London

15.8 (5.4)

30.4 (2.5)*

15.6 (6.6)

13.8 (2.0)

< 0.0001

 Cognitive Impairment Index

22.5 (3.9)

10.4 (3.3)*

22.3 (2.4)

19.3 (2.2)*

< 0.0001

ADHD

 SRT- LTS

32.2 (6.9)

34.9 (7.3)

29.6 (6.7)

30.5 (6.8)

0.50

 SRT - CLTR

25.5 (8.2)

27.3 (5.0)

18.3 (7.8)

22.6 (4.4)

0.51

 SPART

18.3 (4.9)

22.0 (4.2)*

21.2 (4.2)

21.2 (3.7)

0.06

 SDMT

17.1 (5.5)

35.8 (7.2)*

17.4 (11.1)

22.1 (11.4)

0.004

 Trail Making Test A

61.9 (17.3)

38.4 (22.2)*

46.1 (26.2)

31.5 (16.9)

0.51

 Trail Making Test B

160.8 (45.4)

108.7 (61.0)*

204.6 (75.9)

178.0 (131.11)

0.51

 SRT-D

7.1 (2.1)

6.8 (2.0)

6.2 (1.8)

6.6 (1.0)

0.41

 SPART-D

6.0 (2.2)

7.7 (2.0)*

6.9 (2.3)

6.6 (1.2)

0.04

 Tower of London

15.9 (9.1)

30.5 (11.0)*

13.5 (11.3)

17.9 (12.6)

0.27

 Cognitive Impairment Index

23.8 (4.7)

15.3 (5.6)*

23.4 (4.0)

19.3 (3.6)*

0.06

  1. Abbreviations: POMS pediatric onset multiple sclerosis, ADHD Attention Deficit Hyperactivity Disorder, ST specific training, nST non specific training, SRT-LTS Selective Reminding Test Long Term Storage, SRT-CTLR Selective Reminding Test Consistent Long-Term Retrieval, SRT-D Selective Reminding Test–Delayed, SPART Spatial Recall Test, SPART-D Spatial Recall Test–Delayed, SDMT Symbol Digit Modalities Test, CDI Children’s Depression Inventory
  2. *Indicate significant Effect for time (Baseline vs Post – Treatment comparison); p < 0.05