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Table 2 Target levels and interventions for risk factors at the 3-month risk factor assessment

From: Pragmatic trial of multifaceted intervention (STROKE-CARD care) to reduce cardiovascular risk and improve quality-of-life after ischaemic stroke and transient ischaemic attack –study protocol

Condition

Target

Intervention to achieve the targets

Hypertension

BP < 140/90 mmHg

BP < 130/85 mmHg in patients with diabetes, renal impairment or small-vessel disease

Adjustment of anti-hypertensive medication

Information on supportive lifestyle changes

Written recommendations to and intensified management by the GP

Dyslipidaemia

LDL-C < 100 mg/dL

LDL-C < 70 mg/dL in very high-risk patients

Adjustment of statin dosage

Prescription of ezetimibe additionally to high-dose statins (according to guidelines)

Involvement of a lipid-clinic and prescription of PCSK9 inhibitors (according to guidelines)

Individualised recommendations by a dietitian

Diabetes

HbA1c < 7%

Re-evaluation of the therapeutic regime by a diabetes-specialist

Additional management by the GP, re-instruction in correct administration of injectable pharmacological agents

Individualised recommendations by a dietitian

Smoking

Nicotine abstinence

Motivational interviewing and counselling

Provision of informational material

Involvement of a psychiatric specialist for behavioural or pharmacological therapy

Physical inactivity

Physical activity of moderate to vigorous intensity with an average of 40 min at least 3 times per week

Motivational interviewing

Provision of informational material

Non-adherence to drug prescriptions

Adherence to drug prescription (proportion of days covered ≥90%)

Motivational interviewing with information on indication & therapeutic effect of current medication

Simplification of drug-regimes

Home support by nurses and/or relatives

Poor “stroke-knowledge” of patients & family-members or caregivers

 

Information on stroke pathophysiology & individual stroke mechanism

Provision of a book and standardised information material

Post-stroke complicationsa & poor functional outcome

Improvement of QoL

Individualised treatment & prevention of post-stroke complications

Provision of further outpatient or inpatient rehabilitation

Re-assessment on nursing demands, social integration & outpatient care

Involvement of a social worker

  1. BP blood pressure, GP general practitioner, LDL-C low-density lipoprotein cholesterol, PCSK9 proprotein convertase subtilisin/kexin type 9, HbA1c glycated haemoglobin, QoL quality of life
  2. aspasticity, pain, risk of falling, post stroke-depression (PSD), fatigue, anxiety, dysphagia, social deprivation, post-stroke dementia