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Table 5 Odds of readmission in AIS according to demographic, clinical, and care setting characteristics

From: Association between medication-related adverse events and non-elective readmission in acute ischemic stroke

Characteristic Any Readmission p valuea AORb(95% CI) AIS Readmission p valuea AORb(95% CI) Non-AIS Readmission p valuea AORb(95% CI)
Yes n (%) n = 47,170 No n (%)n = 392,512 Yes n (%)n = 6205 No n (%)n = 433,477 Yes n (%)n = 40,965 No n (%)n = 398,717
Age
 <  40 1311 (2.8) 11,567 (2.9) <.001 1.12 (1.00–1.26)* 135 (2.2) 12,743 (2.9) <.001 0.76 (0.55–1.04) 1176 (2.9) 11,702 (2.9) <.001 1.20 (1.06–1.36)**
 40–49 2379 (5.0) 22,793 (5.8)   Reference 365 (5.9) 24,807 (5.7)   Reference 2014 (4.9) 23,158 (5.8)   Reference
 50–59 6212 (13.2) 58,151 (14.8)   0.97 (0.88–1.05) 929 (15.0) 63,434 (14.6)   1.01 (0.83–1.21) 5283 (12.9) 59,080 (14.8)   0.96 (0.87–1.05)
 60–69 9649 (20.5) 85,487 (21.8)   0.93 (0.85–1.01) 1431 (23.1) 93,705(21.6)   1.08 (0.90–1.30) 8218 (20.1) 86,918 (21.8)   0.90 (0.83–0.99)*
 70–79 11,992 (25.4) 91,829 (23.4)   0.97 (0.88–1.06) 1590 (25.6) 102,231 (23.6)   1.12 (0.91–1.37) 10,402 (25.4) 93,419 (23.4)   0.95 (0.86–1.05)
 80–89 11,861 (25.1) 90,080 (22.9)   0.93 (0.85–1.02) 1389 (22.4) 100,551 (23.2)   0.99 (0.81–1.22) 10,472 (25.6) 91,469 (22.9)   0.93 (0.84–1.02)
 90+ 3766 (8.0) 32,605 (8.3)   0.82 (0.74–0.91)*** 366 (5.9) 36,005(8.3)   0.72 (0.56–0.93)* 3400 (8.3) 32,971 (8.3)   0.84 (0.75–0.94)**
Sex
 Female 24,509 (52.0) 201,061 (51.2) 0.087 Reference 3024 (48.7) 222,546 (51.3) 0.013 Reference 21,485 (52.4) 204,085 (51.2) 0.005 Reference
 Male 22,661 (48.0) 191,450 (48.8)   1.03 (1.00–1.07) 3181 (51.3) 210,930 (48.7)   1.07 (0.99–1.17) 19,480 (47.6) 194,631 (48.8)   1.02 (0.99–1.06)
Primary payerc
 Private insurance 5834 (12.4) 70,149 (17.9) <.001 Reference 1002 (16.1) 74,981 (17.3) 0.159 Reference 4832 (11.8) 71,151 (17.8) <.001 Reference
 Medicare 34,216 (72.5) 261,439 (66.6)   1.33 (1.26–1.40)*** 4160 (67.0) 291,495 (67.2)   1.02 (0.90–1.16) 30,057 (73.4) 265,598 (66.6)   1.39 (1.30–1.47)***
 Medicaid 4794 (10.2) 34,297 (8.7)   1.41 (1.32–1.51)*** 636 (10.2) 38,455 (8.9)   1.20 (1.02–1.42)* 4158 (10.2) 34,933 (8.8)   1.44 (1.34–1.55)***
 Self-pay 1264 (2.7) 15,040 (3.8)   1.04 (0.93–1.16) 231 (3.7) 16,072 (3.7)   1.05 (0.81–1.37) 1033 (2.5) 15,270 (3.8)   1.03 (0.92–1.16)
 No charge 169 (0.4) 2139 (0.5)   1.01 (0.72–1.41) 42 (0.7) 2266 (0.5)   1.38 (0.85–2.25) 127 (0.3) 2181 (0.5)   0.92 (0.64–1.34)
Median household income
 $66,000+ 9260 (19.6) 79,543 (20.3) <.001 Reference 1312 (21.1) 87,492 (20.2) 0.014 Reference 7948 (19.4) 80,855 (20.3) <.001 Reference
 $51,000 - $65,999 10,175 (21.6) 89,756 (22.9)   0.97 (0.92–1.02) 1327 (21.4) 98,605 (22.7)   0.90 (0.79–1.03) 8848 (21.6) 91,083 (22.8)   0.99 (0.94–1.04)
 $40,000 - $50,999 12,546 (26.6) 105,950 (27.0)   1.01 (0.96–1.06) 1544 (24.9) 116,952 (27.0)   0.88 (0.78–1.01) 11,002 (26.9) 107,493 (27.0)   1.04 (0.98–1.09)
 $1 - $39,999 14,620 (31.0) 112,048 (28.5)   1.08 (1.03–1.14)** 1952 (31.5) 124,717 (28.8)   1.03 (0.91–1.17) 12,668 (30.9) 114,000 (28.6)   1.09 (1.03–1.15)**
 Missing 569 (1.2) 5214 (1.3)   n/a 71 (1.1) 5712 (1.3)   n/a 498 (1.2) 5285 (1.3)   n/a
Length of stay
 0–7 days 27,070 (57.4) 279,716 (71.3) <.001 Reference 4557 (73.4) 302,229 (69.7) <.001 Reference 22,513 (55.0) 284,273 (71.3) <.001 Reference
 >  7 days 20,100 (42.6) 112,796 (28.7)   1.38 (1.33–1.43)*** 1648 (26.6) 131,248 (30.3)   0.75 (0.68–0.83)*** 18,452 (45.0) 114,444 (28.7)   1.50 (1.44–1.55)***
Discharge disposition
 Routine 13,069 (27.7) 161,864 (41.2) <.001 Reference 2265 (36.5) 172,667 (39.8) <.001 Reference 10,803 (26.4) 164,129 (41.2) <.001 Reference
 Transfer: short-term hospital 1306 (2.8) 7245 (1.8)   1.91 (1.70–2.14)*** 327 (5.3) 8224 (1.9)   3.08 (2.44–3.90)*** 979 (2.4) 7571 (1.9)   1.63 (1.44–1.84)***
 Transfer: other type of facility 22,491 (47.7) 142,394 (36.3)   1.52 (1.45–1.59)*** 2168 (34.9) 162,716 (37.5)   1.06 (0.95–1.19) 20,322 (49.6) 144,562 (36.3)   1.59 (1.51–1.67)***
 Home health care 9693 (20.5) 77,296 (19.7)   1.26 (1.20–1.32)*** 1298 (20.9) 85,691 (19.8)   1.19 (1.07–1.33)** 8395 (20.5) 78,594 (19.7)   1.27 (1.20–1.34)***
 Against medical advice 595 (1.3) 2936 (0.7)   2.41 (2.08–2.79)*** ## ##   3.12 (2.29–4.23)*** 450 (1.1) 3081 (0.8)   2.13 (1.83–2.47)***
 Discharged alive, destination unknown 16 (0.0) 777 (0.2)   0.20 (0.11–0.38)*** ## ##   0.16 (0.02–1.08) 15 (0.0) 779 (0.2)   0.21 (0.11–0.42)***
Comorbidities
 0–2 7125 (15.1) 103,632 (26.4) <.001 Reference 1364 (22.0) 109,392 (25.2) 0.001 Reference 5761 (14.1) 104,995 (26.3) <.001 Reference
 3–4 16,020 (34.0) 150,414 (38.3)   1.36 (1.30–1.43)*** 2400 (38.7) 164,034 (37.8)   1.20 (1.07–1.34)** 13,620 (33.2) 152,814 (38.3)   1.40 (1.32–1.47)***
 5–6 14,413 (30.6) 92,786 (23.6)   1.78 (1.68–1.87)*** 1629 (26.2) 105,571 (24.4)   1.31 (1.16–1.47)*** 12,784 (31.2) 94,415 (23.7)   1.86 (1.75–1.97)***
 7+ 9612 (20.4) 45,680 (11.6)   2.20 (2.08–2.34)*** 812 (13.1) 54,479 (12.6)   1.34 (1.15–1.55)*** 8800 (21.5) 46,492 (11.7)   2.34 (2.19–2.49)***
Bed size of hospital
 Small 6334 (13.4) 58,615 (14.9) <.001 Reference 920 (14.8) 64,028 (14.8) 0.533 Reference 5414 (13.2) 59,535 (14.9) <.001 Reference
 Medium 12,747 (27.0) 107,616 (27.4)   1.04 (0.98–1.11) 1762 (28.4) 118,601 (27.4)   1.02 (0.88–1.17) 10,985 (26.8) 109,379 (27.4)   1.05 (0.97–1.12)
 Large 28,089 (59.5) 226,281 (57.6)   1.08 (1.02–1.15)* 3523 (56.8) 250,847 (57.9)   1.00 (0.88–1.13) 24,566 (60.0) 229,803 (57.6)   1.10 (1.02–1.18)*
Control/ownership of hospital
 Government, non-federal (public) 5348 (11.3) 48,360 (12.3) <.001 Reference 732 (11.8) 52,976 (12.2) 0.081 Reference 4616 (11.3) 49,093 (12.3) <.001 Reference
 Private, not-for-profit (voluntary) 34,592 (73.3) 291,432 (74.2)   1.04 (0.97–1.11) 4529 (73.0) 321,495 (74.2)   1.00 (0.86–1.16) 30,063 (73.4) 295,961 (74.2)   1.04 (0.97–1.12)
 Private, investor-owned (proprietary) 7229 (15.3) 52,720 (13.4)   1.20 (1.12–1.29)*** 944 (15.2) 59,006 (13.6)   1.09 (0.91–1.30) 6286 (15.3) 53,664 (13.5)   1.21 (1.13–1.30)***
Teaching status of hospital
 Metropolitan teaching 30,821 (65.3) 247,949 (63.2) <.001 Reference 3856 (62.1) 274,914 (63.4) 0.161 Reference 26,965 (65.8) 251,806 (63.2) <.001 Reference
 Metropolitan non-teaching 12,662 (26.8) 105,886 (27.0)   0.97 (0.93–1.01) 1786 (28.8) 116,762 (26.9)   1.08 (0.97–1.19) 10,876 (26.5) 107,671 (27.0)   0.95 (0.91–1.00)*
 Non-metropolitan 3687 (7.8) 38,677 (9.9)   0.79 (0.73–0.85)*** 563 (9.1) 41,801 (9.6)   0.92 (0.77–1.11) 3124 (7.6) 39,240 (9.8)   0.77 (0.71–0.84)***
  1. ##Data suppressed - 10 or fewer observations in some cells
  2. Abbreviations: AIS Acute ischemic stroke, AOR Adjusted odds ratio, CI Confidence interval
  3. ***p < 0.001; **p < 0.01; *p < 0.05
  4. aChi-square test
  5. bAdjusted for all factors listed in table
  6. cSome categories excluded due to small sample sizes