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Table 1 Baseline characteristics

From: Diagnostic and prognostic value of the optic nerve sheath diameter with respect to the intracranial pressure and neurological outcome of patients following hemicraniectomy

   Neurological outcome (6 months)
All Unfavorable GOS 1–3 Favorable GOS4–5 p-value
Number of patients 33 20 (60.6%) 13 (39.4%)
Age, y 46.6 ± 14.9 47.9 ± 15.0 46.5 ± 14.1 0.552
Sex (male), n (%) 25 (75.8%) 15 (45.5%) 10 (30.3%) 0.619
Causes of surgery, n (%) 0.474
 Traumatic brain injury 31 (93.9%) 14 (42.4%) 17 (51.5%)
 Hemorrhage stroke 2 (6.1%) 2 (6.1%) 0
Initial Glasgow coma score (GCS) 0.008
 3–8 22 (66.7%) 17 (51.5%) 5 (15.2%)
 ≥ 9 11 (33.3%) 3 (9.1%) 8 (24.2%)  
Initial Pupil light reflex (n %) 0.039
 Both react 20 (60.6%) 9 (27.3%) 11 (33.3%)  
 1 reacts 3 (9.1%) 2 (6.1%) 1 (3.0%)  
 None reacts 10 (30.3%) 9 (27.3%) 1 (3.0%)  
Helsinki CT score 6 ± 3 7 ± 2 4 ± 3 0.013
ICU duration (day) 8 (6–12) 9 (8–13) 7 (3–12) 0. 079
Hospital discharge (day) 19 ± 9 17 ± 8 22 ± 10 0.134
Data during ocular ultrasound performed within 6 h after craniectomy
 ICP (mmHg) 22 (9–27) 26 (24–32) 14 (9–16) 0.668
 MAP (mmHg) 89 (81–97) 89 (82–97) 86 (80–96) 0.337
 CPP (mmHg) 68 ± 18 69 ± 20 67 ± 16 0.812
 Ipsilateral ONSD (mm) 5.9 ± 0.7 6.0 ± 0.7 5.8 ± 0.5 0.164
 Contralateral ONSD (mm) 5.8 ± 0.7 6.1 ± 0.7 5.5 ± 0.7 0.018
  1. CT computerized tomography, ICU intensive care unit, ICP intracranial pressure, MAP mean arterial pressure, CPP cerebral perfusion pressure, ONSD optic nerve sheath diameter, GOS glasgow outcome score, GOS 1 dead, GOS 2 vegetative state, GOS 3 severe disability, GOS 4 moderate disability, GOS 5 back to normal life with or without mild disability