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Table 1 Demographics characteristics stratified by the BRAF and CTNNB1 mutations status in the primary patients and recurrent patients

From: Noninvasive molecular diagnosis of craniopharyngioma with MRI-based radiomics approach

 

BRAF Mutant

N = 12

CTNNB1 Mutant

N = 22

Not Detected

N = 10

P Value

Dataset

PP(N = 9)

RP(N = 3)

PP(N = 15)

RP(N = 7)

PP(N = 8)

RP(N = 2)

1.000

Gender

   

0.770

 Male (%)

9 (75.0)

14 (63.6)

6 (60.0)

 

7

2

12

2

5

1

 

 Female (%)

3 (25.0)

8 (36.4)

4 (40.0)

 

2

1

3

5

3

1

 

Age(year)

   

0.002

 Mean ± SD

47.0 ± 9.9

37.9 ± 15.9

24.9 ± 18.8

 

49.7 ± 8.65

39.0 ± 10.8

39.8 ± 15.9

33.9 ± 16.3

28.0 ± 19.9

12.5 ± 6.4

 

 >18 (%)

12 (100.0)

19 (86.4)

4 (40.0)

 

9

3

13

6

4

0

 

 <18 (%)

0 (0.0)

3 (13.6)

6 (60.0)

 

0

0

2

1

4

2

 

Pathology

   

<0.001

 ACP (%)

0 (0.0)

18 (81.8)

8 (80.0)

 

0

0

13

5

6

2

 

 PCP (%)

12 (100.0)

4 (18.2)

2 (20.0)

 

9

3

2

2

2

0

 
  1. Abbreviations: PP Primary patients, RP Recurrent patients, SD Standard deviation, ACP Adamantinomatous type, PCP Papillary type