rs1234313 and rs45454293 are risk factors of cerebral arterial thrombosis, large artery atherosclerosis, and carotid plaque in the Han Chinese population: a case-control study

Table 4 Association of TNFSF4 rs1234313 polymorphism with types of carotid plaque in patients with ischemic stroke

Genetic model	Comparison	RRR^a vs. controls	p-value	95% CI lower	95%CI Upper
Single plaque
allelic	G vs A	0.995	0.971	0.750	1.320
Dominant	GG/GA vs AA	0.873	0.346	0.659	1.157
genotypic	GA vs AA	0.756	0.149	0.517	1.105
	GG vs AA	1.313	0.381	0.713	2.417
Multi plaque
allelic	G vs A	0.994	0.954	0.813	1.216
Dominant	GG/GA vs AA	0.943	0.534	0.783	1.135
genotypic	GA vs AA	0.898	0.352	0.715	1.127
	GG vs AA	1.143	0.602	0.691	1.893
Thick plaque
allelic	G vs A	1.176	0.216	0.909	1.522
Dominant	GG/GA vs AA	1.141	0.234	0.918	1.417
genotypic	GA vs AA	1.139	0.335	0.875	1.482
	GG vs AA	1.490	0.241	0.765	2.900
Calcification
allelic	G vs A	0.804	0.112	0.615	1.052
Dominant	GG/GA vs AA	0.730	0.022*	0.557	0.956
genotypic	GA vs AA	0.638	0.010*	0.452	0.900
	GG vs AA	0.912	0.767	0.469	1.677

TNFSF4 Tumor necrosis factor super family member 4, RRR relative risk ration, CI Confidence interval; *, p < 0.05, indicating a significant difference

ISSN: 1471-2377