Variables | Younger Group (age < 65 yr) | P Value | Older Group (age ≥ 65 yr) | P Value | ||
---|---|---|---|---|---|---|
Good functional outcome (mRS ≤ 2) (n = 289) | Poor functional outcome (mRS > 2) (n = 38) | Good functional outcome (mRS ≤2) (n = 377) | Poor functional outcome (mRS > 2) (n = 64) | |||
Age (years)a | 57 (51–61) | 58 (52–62) | .169 | 75 (70–80) | 78 (72–83) | .016 |
Sex (male, %) | 191 (66.1%) | 26 (68.4%) | .856 | 225 (59.7%) | 29 (45.3%) | .040 |
Smoking (n,%) | 142 (49.1%) | 25 (65.8%) | .054 | 133 (35.3%) | 15 (23.4%) | .064 |
Hyperlipidemia (n,%) | 156 (54.0%) | 21 (55.3%) | .881 | 105 (27.9%) | 23 (40.0%) | .188 |
Coronary artery disease (n, %) | 16 (5.5%) | 5 (13.2%) | .081 | 33 (8.8%) | 6 (9.4%) | .871 |
Diabetes mellitus (n, %) | 75 (26.0%) | 9 (23.7%) | .846 | 87 (23.1%) | 17 (26.6%) | .633 |
Atrial fibrillation (n, %) | 10 (3.5%) | 6 (15.8%) | .006 | 41 (10.9%) | 15 (23.4%) | .008 |
Previous stroke (n, %) | 18 (6.2%) | 3 (7.9%) | .722 | 56 (14.9%) | 13 (20.3%) | .352 |
Transient ischemic attacks (n, %) | 7 (2.4%) | 2 (5.3%) | .281 | 13 (3.4%) | 2 (3.1%) | .625 |
History of hypertension (n, %) | 168 (58.1%) | 23 (60.5%) | .862 | 270 (71.6%) | 41 (64.1%) | .237 |
Systolic blood pressure (mm Hg)a | 152 (131–170) | 151 (135–165) | .525 | 161 (141–176) | 158 (147–171) | .469 |
Diastolic blood pressure (mm Hg)a | 85 (77–95) | 83 (78–99) | .610 | 80 (71–88) | 77 (67–87) | .276 |
Baseline NIHSS scoresa | 2 (1–3) | 11 (8–15) | ≤.001 | 2 (1–4) | 11 (8–14) | ≤.001 |
TSH (IU/L)a | 1.52 (1.01–2.05) | 1.60 (1.14–1.96) | .951 | 1.73 (1.09–2.45) | 1.36 (0.85–1.98) | .021 |
total T4 (μg/dL)a | 6.37 (5.55–7.23) | 6.88 (5.89–7.82) | .068 | 6.51 (5.79–7.47) | 6.96 (6.03–7.95) | .051 |
total T3 (ng/mL)a | 0.86 (0.73–0.98) | 0.76 (0.63–0.92) | .013 | 0.82 (0.71–0.93) | 0.71 (0.57–0.83) | ≤.001 |
free T4 (ng/dL)a | 1.07 (0.98–1.17) | 1.11 (0.99–1.21) | .257 | 1.10 (1.00–1.20) | 1.13 (1.03–1.29) | .040 |
free T3 (pg/mL)a | 2.59 (2.31–2.93) | 2.40 (2.01–2.66) | .001 | 2.49 (2.20–2.77) | 2.21 (1.92–2.53) | ≤.001 |
Initial WBC count (×109/L)a | 7.10 (5.90–8.95) | 8.60 (6.28–10.60) | .134 | 6.60 (5.60–8.30) | 7.80 (6.30–8.40) | .175 |
Glucose on admission (mmol/L)a | 7 (5.78–9.24) | 8.19 (6.06–13.36) | .072 | 7.04 (5.81–9.36) | 7.29 (5.85–10.72) | .516 |
C–reactive protein (mg/dL)a | 1.40 (0.80–2.80) | 1.7 (0.80–2.40) | .366 | 2.10 (0.90–5.90) | 3.45 (1.25–8.13) | .876 |