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Table 1 Characteristics of ischemic stroke patients with or without carotid stenosis

From: The TXA2R rs1131882, P2Y1 rs1371097 and GPIIIa rs2317676 three-loci interactions may increase the risk of carotid stenosis in patients with ischemic stroke

Characteristics

Carotid stenosis (n = 236)

Non-carotid stenosis (n = 378)

P value

Age (years)

69.1 ± 12.8

68.8 ± 15.9

0.607

Men (n, %)

142 (60.2)

222 (58.7)

0.597

Hypertension (n, %)

192 (81.4)

301 (79.6)

0.796

Diabetes mellitus (n, %)

81 (34.3)

124 (32.8)

0.379

Previous MI (n, %)

4 (1.7)

6 (1.6)

0.996

Cigarette smoking (n, %)

94 (39.8)

148 (39.1)

0.962

Alcohol intake (n, %)

108 (45.8)

170 (45.0)

0.896

Body mass index (kg/m2)

24.2 ± 3.7

24.0 ± 4.2

0.943

Hyperlipidemia(n, %)

129 (54.7)

199 (52.6)

0.467

Fasting bloodglucose (mM)

6.8 ± 3.2

6.6 ± 4.3

0.411

Hemoglobin A1c (%)

6.4 ± 2.8

6.2 ± 2.7

0.357

Homocysteine (mM)

15.1 ± 5.5

14.7 ± 5.8

0.108

Previous drugs treatments (n, %)

 Antihypertensive drugs

131 (55.5)

208 (55.0)

0.996

 Hypoglycemic drugs

60 (25.4)

100 (26.5)

0.994

 Statins

50 (21.2)

81 (21.4)

0.999

 Antiplatelet drugs

71 (30.1)

115 (30.4)

0.998

Platelet aggregation (%)

 AA-induced

90.3 ± 13.2

86.2 ± 14.7

< 0.001

 ADP-induced

89.7 ± 13.4

86.3 ± 13.6

0.002

Platelet-leukocyte aggregates (%)

 Leukocyte

26.8 ± 6.5

24.2 ± 6.6

< 0.001

 Neutrophil

27.1 ± 6.6

24.3 ± 7.2

< 0.001

 Monocyte

26.7 ± 5.9

23.7 ± 6.5

< 0.001

 Lymphocyte

26.3 ± 6.3

24.4 ± 6.4

< 0.001

  1. MI myocardial infarction, AA arachidonic acid, ADP adenosine diphosphate