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Table 5 Overview of experimental flow for the drug study. Conditions and task orders are further outlined in Table 6

From: Michigan Neural Distinctiveness (MiND) study protocol: investigating the scope, causes, and consequences of age-related neural dedifferentiation

 

Drug Study

Timepoint:

Enrolment

Session 1

Session 2

Enrolment:

 Eligibility screen

X

  

 Informed consent

X

X

 

 Condition Allocation

X

  

Intervention:

 Groups 1A & 1B Placebo

 

X

 

 Groups 1A & 1B Lorazepam

  

X

 Groups 2A & 2B Placebo

  

X

 Groups 2A & 2B Lorazepam

 

X

 

MRI:

 Groups 1A & 2A fMRI Tasks (visual-motor)

 

X

 

 Groups 1A & 2A fMRI Tasks (motor-visual)

  

X

 Groups 1B & 2B fMRI Tasks (visual-motor)

  

X

 Groups 1B & 2B fMRI Tasks (motor-visual)

 

X

 

 All Groups fMRI Resting State

 

X

X