A ketogenic diet normalizes interictal cortical but not subcortical responsivity in migraineurs

BMC Neurology

Table 1 Baseline clinical and demographic characteristics of the study participants

Characteristics	HV (n = 18)	M-tot (n = 18)
Women (n)	16	16
Age (years)	39.7 ± 10.1	40.8 ± 11.7
Duration of migraine history (years)		21.0 ± 11.5
		Before	After 1-month KD
Attack frequency/month (n)		4.7 ± 2.5	1.9 ± 2.1 **
Attack duration (hours)		42.8 ± 24.0	17.9 ± 20.6 *
Disability (0–3)		2.7 ± 0.5	1.4 ± 1.1 **
Days since the last attack (n)		9.1 ± 8.5	12.4 ± 11.0
Body mass index (BMI)	26.2 ± 4.5	26.7 ± 4.6	25.3 ± 4.6

Data are expressed as means ± SD. Disability is a scale of self-perceived headache related disability (0= no disability; 1= mild disability; 2= partial disability; 3= total disability). * = p < 0.01 ** = p < 0.001 before vs. after 1-month ketogenic diet. HV Healthy Volunteers, M-tot Total of Migraine patients

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