Outcome domain | Test | Time point |
---|---|---|
Primary outcome measure | ||
 Cerebellar ataxia severity | SARA (absolute change from baseline) | T1 |
Secondary outcome measures | ||
 Cerebellar ataxia severity | SARA (% of patients with a decrease of ≥ 1.5 points) | T1 |
 Cerebellar ataxia severity | SARA score and subscores | T0 after tDCS, T2-T4 |
 Gait speed | 8 m walk test | T0 after tDCS, T1-T4 |
 Articulation speed | PATA repetition rate | T0 after tDCS, T1-T4 |
 Upper limb dexterity | 9-hole peg test | T0 after tDCS, T1-T4 |
 Extracerebellar signs | INAS count | T1-T4 |
 Postural sway | Static posturography | T0 after tDCS and T1 |
 Quality of life | EQ-5D-5L | T1-T4 |
 Depression | PHQ-9 | T1-T4 |
 Mood states | POMS 32-item version | T1-T4 |
 Cognition and affect | CCAS scale (total score and number of ‘fails’) | T1-T4 |
 Activities of daily living | FARS part II | T1-T4 |
 Medical consumption | iMCQ | T4 |
 Motor learning | Delay EBC (acquisition of CRs) | T1 |
 CBI | Transcranial magnetic stimulation | T1 |
 tDCS-related side effects | Open question | T1 |
 Correct randomization | Patients’ thoughts about treatment allocation | T1 |