Table 1 Clinical and biochemical characteristics of surviving and non-surviving MMCAI patients

Age (years) - median (p 25–75)

59 (47–68)

63 (53–70)

Diabetes mellitus - n (%)

4 (11.8)

9 (26.5)

Gender female - n (%)

14 (41.2)

13 (38.2)

Arterial hypertension - n (%)

19 (55.9)

16 (47.1)

Chronic renal failure - n (%)

2 (5.9)

2 (5.9)

COPD - n (%)

1 (2.9)

1 (2.9)

Heart failure - n (%)

1 (2.9)

1 (2.9)

APACHE-II score - mean ± SD

20.38 ± 6.89

22.85 ± 5.93

GCS score - median (p 25–75)

7 (6–8)

6 (3–7)

Temperature (°C) - median (p 25–75)

36.4 (36.0–37.0)

36.9 (36.0–37.3)

Creatinine (mg/dl) - median (p 25–75)

0.80 (0.60–1.13)

1.00 (0.70–1.25)

Sodium (mEq/L)- median (p 25–75)

139 (136–145)

140 (139–145)

Bilirubin (mg/dl) - median (p 25–75)

0.60 (0.40–0.83)

0.60 (0.33–1.10)

Glycemia (g/dL) - median (p 25–75)

127 (100–170)

136 (118–162)

Lactic acid (mmol/L)-median (p 25–75)

1.20 (0.90–1.70)

1.55 (1.00–2.70)

PaO2 (mmHg) - median (p 25–75)

156 (105–293)

115 (94–267)

PaO2/FI0₂ ratio - mean ± SD

298 ± 116

262 ± 96

INR - median (p 25–75)

1.06 (1.00–1.20)

1.20 (1.01–1.31)

Fibrinogen (mg/dl) - median (p 25–75)

443 (416–489)

419 (337–631)

aPTT (seconds) - median (p 25–75)

28 (25–30)

27 (26–32)

Leukocytes-median*10³/mm³ (p 25–75)

12.4 (9.6–16.9)

13.9 (9.7–20.1)

Hemoglobin (g/dL) - mean ± SD

12.60 ± 1.73

12.82 ± 1.96

Platelets - mean ± SD

225242 ± 84667

179382 ± 61975

Haemorrhagic transformation - n (%)

7 (20.6)

6 (17.6)

Volumen infarction (ml) - mean ± SD

162 ± 82

182 ± 110

Midline shift (mm) - mean ± SD

7.47 ± 6.14

9.09 ± 6.60

Thrombolysis - n (%)

11 (32.4)

10 (29.4)

Decompressive craniectomy – n (%)

9 (26.5)

7 (20.6)

MMP-9 (ng/mL) - median (p 25–75)

839 (719–1192)

708 (396–949)

TIMP-1 (ng/mL) - median (p 25–75)

206 (173–262)

375 (248–468)