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Table 2 Baseline characteristics and HOMA-IR in relation to stroke severity

From: Homeostasis model assessment of insulin resistance and outcome of ischemic stroke in non-diabetic patients - a prospective observational study

 

Stroke severity

Severe

Moderate

Mild

n

Mean ± SEM

n

Mean ± SEM

n

Mean ± SEM

p-value

Sex (ratio m/f)

114

1.39 ± 0.05

167

1.37 ± 0.04

160

1.36 ± 0.04

0.59

Age (years)

114

56.1 ± 0.95

167

57.0 ± 0.80

160

55.2 ± 0.89

0.49

Hypertension (%)

112

57 ± 4.7

166

64 ± 3.7

160

52 ± 4.0

0.39

Smoking (%)

113

48 ± 4.7

167

30 ± 3.6

160

42 ± 3.9

0.34

Atrial fibr (%)

113

14 ± 3.6

149

11 ± 2.5

150

8 ± 2.2

0.11

CAD (%)

97

16 ± 3.5

167

10 ± 2.4

158

9 ± 2.3

0.071

BMI (kg/m2)

110

25.6 ± 0.42

166

26.7 ± 0.36

157

25.7 ± 0.29

0.86

Acute LDL (mmol/L)

98

3.22 ± 0.10

147

3.40 ± 0.08

150

3.39 ± 0.08

0.18

Acute CRP (mg/L)

113

16.4 ± 2.32

164

10.7 ± 1.77

156

8.65 ± 0.97

0.002

Acute p-glucose

114

6.14 ± 0.15

167

5.64 ± 0.09

160

5.41 ± 0.04

< 0.001

3-month p-glucose

106

5.21 ± 0.05

171

5.23 ± 0.05

152

5.17 ± 0.05

0.69

Acute insulin

114

15.2 ± 1.28

167

15.1 ± 1.10

160

12.9 ± 1.05

0.18

3-month insulin

106

12.5 ± 0.88

171

13.4 ± 0.81

152

10.5 ± 0.48

0.03

Acute HOMA-IRa

114

3.22 ± 0.41

167

2.95 ± 0.29

160

2.47 ± 0.28

0.02

3 month HOMA-IRa

106

2.48 ± 0.24

171

2.50 ± 0.21

152

2.00 ± 0.13

0.02

  1. The patients were categorized using the acute National Institutes of Health Stroke Scale (NIHSS) as having severe (NIHSS score 5.91–25.25), moderate (NIHSS score 1.61–5.90) or mild (NIHSS stroke 0–1.60) stroke. If not otherwise stated, data are shown as means (if not otherwise stated) and ± SEM. In addition, n is shown as numbers vary due to missing data. Differences between severe and mild stroke were examined by ANOVA. ns not significant, LDL low-density lipoprotein, BMI body mass index, CRP C-reactive protein, CAD History of Coronary Artery Disease before the event; Atrial fibr, Atrial Fibrillation before the event; Smoking, Current Smoking. agiven as geometric mean and ± SEM