Fig. 1From: A pathogenic PSEN1 Trp165Cys mutation associated with early-onset Alzheimer’s diseaseBrain functional and structural neuroimaging data of the proband at diagnosis. a. Axial FLAIR, coronal, and sagittal T1 images of brain MRI, arrows pointing at left-dominant bilateral temporal lobe atrophy. b. FDG-PET, arrows pointing at hypometabolism in left temporal cortex, right anterior temporal cortex and bilateral frontal cortexBack to article page