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Table 2 The FSHD-COM

From: Clinical trial readiness to solve barriers to drug development in FSHD (ReSolve): protocol of a large, international, multi-center prospective study

Region

ITEM

References

Leg function

Sit to stand

without hands

[51,52,53]

6 Minute Walk

[54,55,56]

Self-selected gait speed

[57,58,59]

Go 30′

[49, 55, 60]

Ascend/ descend stairs

[49, 55, 60]

Shoulder / arm function

Shoulder Abduction (R/L)

[18, 60, 61]

Shoulder Forward Flexion (R/L)

[18, 60, 61]

Elbow Flexion (R/L)

[18, 60, 61]

Don/doff Coat

[62]

Trunk function

Pick up a penny from floor

[62]

Sit up with feet held

[4]

Supine to sit

[4]

Hand function

Hand Grip Force Men

[49, 63,64,65]

Hand Grip Force Women

[49, 63,64,65]

Balance

TUG: Timed up and Go

[66, 67]

  1. The FSHD-COM is an 18-item instrument comprised of individually validated motor tasks. More weight is given to leg function and shoulder/arm function which are the two most frequently cited areas of patient concern (table modified from Eichinger et al. [21])