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Fig. 2 | BMC Neurology

Fig. 2

From: Mid-life serum Vitamin D concentrations were associated with incident dementia but not late-life neuropsychological performance in the Atherosclerosis Risk in Communities (ARIC) Study

Fig. 2

Association between mid-life 25(OH)D (1990-1992) and Later Life. Neuropsychological Test Performance (2011-2013): ARIC-NCS. DWR=Delayed word recall test; LM=Logical memory; IL=Incidental learning symbol; WFT=Word fluency test; DSS=Digit symbol substitution; DSB=Digit span backwards; FAQ=Functional activities questionnaire; 4 MS=Time to walk 4 meters; GS=Grip strength; SPPB=Short Physical Performance Battery; CES-D=Center for Epidemiologic. Studies Depression; MMSE=Mini-mental state exam. aA higher value indicates a more favorable performance/measure; b a lower value indicates a more favorable performance/measure. Results were derived from multivariable linear regression models. Figure presents the adjusted difference in neuropsychological performance for intermediate 25(OH)D (20-29 ng/ml) [shown in black circles] and deficient vitamin D (<20 ng/ml) [shown in red circles], compared to sufficient 25(OH)D ≥30 ng/mL as reference. Models were adjusted for age, sex, race/center, educational, body mass index, smoking status, alcohol consumption, physical activity, and APOE ε. To covert 25(OH)D from ng/mL to nmol/L, multiply by 2.496

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