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Table 5 The association between rs4261436, rs17522122 and astrocytoma patient OS and PFS

From: Impact of AKAP6 polymorphisms on Glioma susceptibility and prognosis

SNP ID

Genotype

OS

PFS

Log-rank p

SR (1−/3-year)

HR (95%CI)

p

Log-rank p

SR (1−/3-year)

HR (95%CI)

p

rs4261436

TT

0.038

0.258/0.033

1.00

 

0.176

0.152/−

1.00

 

TC

0.367/0.116

0.70 (0.49–0.99)

0.045

0.178/−

0.75 (0.53–1.07)

0.116

CC

0.356/0.111

0.81 (0.64–1.02)

0.078

0.267/−

0.88 (0.70–1.12)

0.308

rs17522122

GG

0.025

0.268/0.049

1.00

 

0.053

0.137/−

1.00

 

GT

0.352/0.106

0.75 (0.59–0.95)

0.016

0.190/−

0.79 (0.55–1.13)

0.686

TT

0.341/0.042

0.78 (0.54–1.12)

0.818

0.268/−

0.78 (0.62–0.99)

0.038

  1. OS Overall survival, PFS Progression free survival, SR Survival rate, HR Hazard ratio, 95% CI 95% Confidence interval
  2. Log-rank p values were calculated using the Chi-Square test
  3. Bold values indicate statistical significance (p < 0.05)